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19 Cards in this Set
- Front
- Back
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adaptive immunity
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that part of the immune system that is specific and has memory- T cells, B cells
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antibodies
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molecules that are secreted by plasma cells. They bind antigen in a specific manner.
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antigen
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molecules that have specific sequences that illicit adaptive immune responses
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antigenicity
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a property of molecules to which an adaptive immune response can be generated
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antigenic determinant
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a particular component of an antigen that is recognized by unique lymphocyte receptors
(that component of an antigen that is recognized by B cells or T cells - T cells only recognize antigens displayed with MHC |
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Bursa of Fabricius
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tissue where B cells mature from progenitor cells (in chickens)
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complement
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a host defense system consisting of soluble and membrane bound proteins
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chemokines
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small molecules that attract cells to a particular region.
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cytokines
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molecules that are secreted primarily by cells of the immune system.
These molecules play an important role in regulation of immune responses. |
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follicle associated epithelium
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region of the lumenal epithelium that is not covered by mucus
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germinal center
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component of a follicle where antigen induced B cell differentiation occurs.
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hapten and carrier
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hapten - a small molecule (less than 6kD) that is not immunogenic unless it binds to a protein; (carrier);
Carrier - protein to which a small molecule (less than 6kD, hapten) has bound permitting an anti-hapten immune response. |
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hematopoiesis
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the differentiation of various cell types from a pluripotent stem cell. Cytokines
play an important role in this process. |
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immunogenicity
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– Refers to a molecule that
can serve as the stimulus for an adaptive immune response. a term used synonymously with the CLASSICAL definition of antigenicity. |
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innate immunity
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component of immunity in which cells and effectors do not have memory, nor receptors specific for
an epitope |
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mitogen
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polyclonal activator
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periarteriolar lymphatic sheath (PALS)
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region containing the white pulp; predominant immune cell is the T cell and where primary T cell
responses can occur. |
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white pulp
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region of the spleen within PALS; predominant immune cell is the T cell and where primary T cell
responses can occur. |
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tolerance (self tolerance)
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refers to the fact that the immune system is not pathologically activated in the presence of its own
antigens. |
