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10 Cards in this Set

  • Front
  • Back
Exogenous Ag includes all of the following EXCEPT:
a. bacterial toxins

b. parasites

c. bacteria

d. virus

e. ragweed pollen
D
Human class MCH I a chain molecules are:

a. b2-microglobulin

b. HLA-A, HLA-B, HLA-C

c. HLA-DR, HLA-DP, HLA-DQ

d. li
B
Signaling to a Tc cell that a liver cell in infected with hepatitis virus depends on:

a. binding of li to MHC I until the peptide is loaded

b. binding of TCR on Tc cell to MHC II on the infected cell

c. binding of processed Ag to liver cell MHC I

d. both b and c are correct
C
Endogenous Ag presentation requires delivery of Ag peptides to the ER by:

a. MHC I and li

b. calnexin and tapasin

c. HLA-DM

d. leader protein sequences

e. TAP-1 and TAP-2
E
Exogenous Ag is processed:

a. in acidified endosomes

b. in the presence of b2-microglobulin

c. by the cytosolic processing pathway

d. by every nucleated cell
A
Ag binding by MHC I:

a. accomodates many different peptides around 10 amino acids in size

b. preferentially binds peptides 13-18 amino acids in length

c. occurs at a site formed by the folding of a1 and b2-microglobulin

d. occurs only on APCs

e. a and c are correct
A
True or False

If a family has 4 children, no two of them will have the same MHC genotype
FALSE
True or False

MHC I expression is associated with stimulation of Ab production
FALSE
True or False

MHC I and MHC II are less Ag specific than Igs.
TRUE
A relative risk ratio (RR) equal to 1 means you have a 99% chance of developing a particular autoimmune disease relative to the rest of the population.
A relative risk ratio (RR) equal to 1 means you have a 99% chance of developing a particular autoimmune disease relative to the rest of the population.