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32 Cards in this Set
- Front
- Back
- 3rd side (hint)
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Innate Immune System |
Non-specific |
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Components of the innate immune system: |
skin, inflammatory response, NK cells, interferons, and complement system. |
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Naural killer cells |
small subset of lymphocytes |
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Interferons |
soluble proteins that elicit other cells to respond |
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Complement system |
group of proteins in blood |
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Adaptive immune system |
responds specifically to the foreign body/antigent |
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Components of the adaptive immune system |
Humoral immune system, cell mediated immune system |
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Humoral Immune System |
Antigen to antibody complex |
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Most important feature of immune system: |
it does not destroy its own cells |
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Immediate hypersensitivity |
Ex. allergies, and anaphylactic shock |
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Antibody-mediated diseases |
Ex. autoimmune hemolytic anemia |
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Immune complex disease |
Ex. Glomerulonephritis |
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T cell-mediated disease |
Ex. dog has allergic reaction to contact of plastic food bowl |
Humans reaction to poison ivy |
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Lymphoma |
tumor characterized by uncontrolled proliferation of lymphocytes |
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Passive Immunity |
Receive maternal antibodies, and antibodies produced in a donor by injection |
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Immunization |
Injection of microorganisms to elicit antibody production but not causing the disease |
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Attenuated |
Weakened but alive vaccination |
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Inactivated |
Killed vaccination |
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Serology |
The science of detection and measurement of antibodies or antigens |
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Enzyme-Linked Immunosorbent Assay |
Test for heartworm, Felv/FIV, and parvo |
ELISA |
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CELISA |
Tests for equine infectious anemia |
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Rapid Immunomigration Lateral flow immunassay |
Ex. Heska Solo test for HW antigens in dogs |
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Immunodiffusion |
Visible band of precipitation occurs when antibodies present. Ex. Johne's disease |
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Coombs Test Antiglobulin test |
Detects inappropriate antibodies such as ones agains the bodys own tissue |
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Intradermal tests |
Diagnoses allergies through injection of allergens and monitoring for allergic reaction |
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Antibody titers |
Distinguishes between active infection and prior exposure to certain antigens |
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DEA 1.1 subgroups |
Blood group in dogs that has the most severe reactions and will occur within an hour of transfusion. |
~50% of dogs have this blood type |
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Type B |
Blood group in cats that is seen a lot in purebreds and certain geopraphic areas. |
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Type A |
Majority of cats have this blood group. |
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Advantages to cultures |
Increased sensitivity, increased specificity. |
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Disadvantages to cultures |
Contamination (false positives), requires high lelvel of technical expertise. |
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Polymerase Chain Reaction |
test produces many copies of a DNA molecule |
PCR |
