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21 Cards in this Set
- Front
- Back
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Adaptive Immunity
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Memory/specific aspect of the immune system i.e. T cells & B cells
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Antibodies
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molecules secreted by plasma cells, bind antigen in a specific manner
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Antigen
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adaptive immune response generated sequences to said molecules
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Antigenicity
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a property of molecules to which an adaptive immune response can be generated
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Antigenic Determinant
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component of an antigen recognized by unique lymphocyte receptors i.e. recognized by B and T cells
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Bursa of Fabricius
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tissue where B cells mature from progenitor cells (in chickens)
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Complement
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host defense made up of soluble and membrane bound proteins
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Chemokines
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small molecules originally identified b/c of their role in attracting cells to a particular region
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Cytokines
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molecules secreted primarily (not exclusively) by cells of the immune system. Play an important role in the activation and down regulation of immune responses
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Determinant
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(a.k.a. epitope) part of a macromolecule recognized by the immune system, specifically by antibodies, B cells, or T cells.
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Epitope
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a.k.a. antigenic determinant, the part of a macromolecule recognized by the immune system, specifically by antibodies, B cells, or T cells.
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Follicle associated epithelium
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region of lumenal epithelium not covered by mucus
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Germinal center
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follicle component where antigen induced B cell differentiation has occurred
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Hapten and carrier
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small molecule that is NOT immunogenic UNLESS it binds to a protein
carrier- a protein to which a hapten molecule has bound permitting an anti-hapten immune response |
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Hematopoiesis
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differentiation of various cell types from pluripotent stem cell *cytokines play an important role in this process
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Immunogenicity
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a molecule that can serve as the stimulus for an adaptive immune response
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Innate immunity
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immunity component where cells and effectors do not have memory/receptors for an epitope
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Mitogent
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polyclonal activator
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Periarteriolar Lymphatic Shealth (PALS)
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region containing white pulp (SPLEEN)
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White Pulp
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splenic region within PALS, dominant immune cell is T cell i.e. location of primary T cell response
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Tolerance (self tolerance)
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the immune system is not pathologically activated in the presence of its own antigens
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