Immunology Review

Front 1

Anatomical activation of mature B-cells

Back 1

B cell zones of lympoid tissue

Front 2

Leukocyte tethering molecule

Back 2

integrins

Front 3

Immune mediated tissue damage

Back 3

hypersentivity

Front 4

predominant version of TCR in adaptive immunity

Back 4

alpha and beta receptor

Front 5

number of CDRs in B-cell receptors

Back 5

6

Front 6

Induce acute phase response

Back 6

IL-6, TNF, IL-1

Front 7

Ligand expressed on CD4+ T-cells that makes APC better at stimulating T-cells

Back 7

CD40 L

Front 8

TCR alpha chain

Back 8

V, J

Front 9

Involved in inflammatory disorders

Back 9

Th17

Front 10

Fc receptor involved in ADCC

Back 10

FCΎRIII (CD16)

Front 11

Th17 secretes

Back 11

IL-17, IL-22

Front 12

Responsible for delayed type hypersensitivity

Back 12

Macrophages

Front 13

Where are T-cells found in the spleen?

Back 13

Periarteriol XXX

Front 14

Class 1 MHC genes

Back 14

HLA - A, B, C

Front 15

Class 2 MHC genes

Back 15

HLA - DP, DQ, DR

Front 16

Pro-inflammatory cytokines that target endothelium

Back 16

TNF, IL-1

Front 17

Cytokine that promotes switch to IgA

Back 17

TGFβ

Front 18

T-cell accessory molecule involved in adhesion

Back 18

LFA-1, VLA-4

Front 19

Homing molecules on activated T-cells

Back 19

E and P selectin ligand, LFA-1, VLA-4, CXCR3

Front 20

Which T cell population defends against extracellular pathogens?

Back 20

Th2

Front 21

Stablizes C3bBb complex on pathogen surface

Back 21

properdin

Front 22

Adhesion molecules on endothelium that mediate leukocyte rolling

Back 22

E and P selectins

Front 23

Binds to dimeric IgA and facilitates transcytosis

Back 23

Poly-Ig receptor

Front 24

MHC restriction

Back 24

Recognition by T-cells of peptides bound to one's own MHC

Front 25

Enzymes that cleave and activate caspases

Back 25

Granzymes

Front 26

Stage of B cell with recombined heavy chain and μ RNA and surrogate light chain

Back 26

Pre-B cell

Front 27

Intraepithelia lymphocytes that are early sentinels of bacterial infection

Back 27

Gamma delta T-cells

Front 28

Receptor that mediates antibody feedback

Back 28

FcgammaRII

Front 29

CD8 binding site of MHC 1 Molecule

Back 29

alpha3

Front 30

Cytokines that down-regulate the immune response

Back 30

IL-10

Front 31

Components of B-cell co-receptor complex

Back 31

CR2 (CD21), CD19, CD81

Front 32

Basis of X-linked hyper-IgM syndrome

Back 32

Defective CD40L

Front 33

Signature cytokines of Th1

Back 33

IFNgamma, TNF, IL-2

Front 34

Mechanisms of damage in DTH

Back 34

Macs, CTLS, granulomatous inflammation

Front 35

Gene segments in variable region of Ig heavy chain and T-cell beta chain

Back 35

v,d,j

Front 36

professional APCs

Back 36

Dendritic cells, macs, b-cells

Front 37

examples of pathogen associated molecular patterns

Back 37

LPS, PD, lipoteichoic acid, viral RNA, fungal mannans

Front 38

T-cell accessory molecules involved in negative regulation of activated T-cells

Back 38

CTLA-4

Front 39

Which cells express MHC 1?

Back 39

All nucleated cells

Front 40

mycobacteria-induced mechanism of immune evasion

Back 40

inhibit phagolysosome fusion

Front 41

cytokines that drive development of Th1

Back 41

IL-12, IFN-gamma

Front 42

Enzymes responsible for somatic recombination

Back 42

VDJ recombinase (RAG1 and RAG2)

Front 43

CD4 binding site of MHC2

Back 43

Beta2

Front 44

b-cell population that resides in the mucosa and peritoneum

Back 44

B-1 B cells

Front 45

Fc receptor involved in down-regulation of B cell activity

Back 45

Fc-gamma-R2IIb (CD32)

Front 46

Defense against ingested microbes

Back 46

Th1

Front 47

anti-viral cytokines

Back 47

Type 1 IFN