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7 Cards in this Set
- Front
- Back
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TLR
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-epithelia, mono/macrophage, DC, granulocytes, NK, lymphocytes
-recognize bacterial repeating components (RNA, DNA, LPS) -activation of transcription factor NFkB -activation and recruitment |
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NOD
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Innate immune receptor
-cytoplasm of host cells -recognize internalized bacteria -mediates recruitment, secretion of defensins -activates NFkB -most common in plants |
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NKG2D
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NK cells, CD8 T cells
recognizes injured/infected cells to induce apoptosis |
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NK-KIR
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killer inhibitory receptors
NK cells -recognize MHC1. MHC1 suppression by virus causes NK activation/killing. |
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CR3
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opsin-binding receptor on macrophages.
-recognizes C3b |
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LFA-1, I-CAM
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Responsible for adhesion between T cells, monocytes and B cells
-LFA-1 is an Integrin that requires binding to fully activate on T cells |
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RIG
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Binds Viral components to activate IFN-a and IFN-b production/release
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