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10 Cards in this Set
- Front
- Back
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Chronic granulomatous disease |
Group of neutrophil disorders Lack of NADPH oxidase inhibits phagocytes producing reactive oxygen species Causes recurrent pneumonias and abscesses: - Staph aureus - Fungal infections |
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Chediak-Higashi syndrome |
AR neutrophil disorder Microtubule polymerisation defect leading to decreased phagocytosis Features: - Partial albinism - Peripheral neuropathy - Recurrent bacterial infections Pathology: Giant granules in neutrophils and platelets |
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Leukocyte adhesion deficiency |
AR neutrophil disorder Defect of LFA-1 intigrin (CD18) protein Features: - Delayed umbilical sloughing - Recurrent bacterial infections - Absense of pus at infection sites |
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Common variable immunodeficiency |
B-cell disorder |
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Bruton's congenital agammaglobulinaemia |
B-cell disorder |
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Selective IgA deficiency |
B-cell disorder |
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DiGeorge syndrome |
T-cell disorder |
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Severe combined immunodeficiency |
Combined B and T-cell disorder |
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Ataxia telangectasia |
Combined B and T-cell disorder |
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Wiskott-Aldrich syndrome |
Combined B and T-cell disorder |
