Immunology Exam 3 2010

Front 1

members of the S. pyogenes species are almost always _______-hemolytic.

Back 1

alpha or beta

Front 2

Streptococcus pyogenes is the most common causative agent of?

Back 2

pharyngitis

Front 3

Important consequences of an S pyogenes infection include?

Back 3

acute rheumatic fever and poststreptococcal glomerulonephritis

Front 4

A characterisitic of necrotizing fasciitis is that it

Back 4

flesh eating, caused by streptococcus pyogenes, destoys tissue covering the muscvles

Front 5

The R antigen found on the fimbriae of pyogenes

Back 5

has no known biological role

Front 6

M protien

Back 6

is major virulence factor of streptococcus pyogenes

Front 7

streptolysin O is

Back 7

nonantigenic

Front 8

streptolysin S is

Back 8

detected y DNA analysis

Front 9

an elevated antistreptolysin O (ASO) titer indicates

Back 9

Chronic streptococcal infection

Front 10

most streptococcas pyogenes infections demonstrate a rise in antibody titer in

Back 10

2 days

Front 11

serologic testing for S pyogenes for acute and convalescent specimens should be collected _______ apart

Back 11

24 hrs

Front 12

M protien contributes to S pyogenes invasiveness because it

Back 12

impedes phagocytosis

Front 13

shock like symptoms can be produced by high levels of

Back 13

S pyogenes superantigens and cytokines

Front 14

Epstien bar virus EBV is a

Back 14

dna herpes virus
harbored by B lymphocytes in latent infections
most ubiquitous virus known to man

Front 15

in infectious mononucleosis, EBV

Back 15

infects B lymphocytes
produces lymphocytes in perif blood with T cell characteristics
induces a cytotoxic response against infected B lymphs

Front 16

EBV is transmitted primarily by

Back 16

close contact with infectious oral-pharyngeal secretions

Front 17

EBV is ussually manifested by

Back 17

young children

Front 18

IgM type of heterophil antibodies ussually appear during the _______ phase of infectious mono

Back 18

acute

Front 19

% that does not produce heterophil antibodies

Back 19

10-20%

Front 20

Viral capsid antigen VCA is produced by

Back 20

infected B lymphs

Front 21

Anti-VCA immunoglobulin G (IgG) is ussually detected within

Back 21

4-7 days

Front 22

stages of mono characterized by antibody EBNA

Back 22

recent (acute) infection
Reactivation of latent infection

Front 23

The monoslide test is based on agglutination of

Back 23

horse erythrocytes

Front 24

the use of horse erythrocytes in the slide test increases the

Back 24

readability, sensitivity, specifity

Front 25

in rapid monoslide testing a false positive result can be caused by

Back 25

all the above

Front 26

distinguishes between heterophil antibdies: uses beef erythrocytes, guini pig kidney cells, and sheep erythrocytes

Back 26

Paul-Bunnell screening test

Front 27

detects heterophil antibodies and uses horse erythrocytes

Back 27

Davidshon differential test

Front 28

detects heterophile antibodies and uses sheep erythrocytes

Back 28

monoslide agglutination test

Front 29

Hep B virus structure from inside out

Back 29

e antigen
viral DNA
core antigen
surface antigen

Front 30

Acquired rubella is also known as

Back 30

german measles and the 3 day measles

Front 31

Rubella is transmitted by

Back 31

respiratory secretions

Front 32

immunity to rubella results from

Back 32

contraction and vaccination

Front 33

the risk of fetal anomalies in maternal rubella is highest at the

Back 33

first trimester

Front 34

percentage of infants infected in utero fail to survive beyond 18 months

Back 34

10-20%

Front 35

IgG rubella antibody in concentration of 1:8 or greater indicates

Back 35

past infection and clinical protection against future rubella infection

Front 36

Diagnosis of congenital rubella infection can be determined by measuring

Back 36

IgM levels in the neonate

Front 37

rubella cannot be cultured

Back 37

true

Front 38

in a patient with primary rubella infection, the appearance of _______ is associated with the manifestation of clinical signs and symtoms whern present

Back 38

IgM

Front 39

rubella peak levels at

Back 39

10-14 days

Front 40

and diminish in concentration over the next

Back 40

4-5 weeks

Front 41

acute hepatitis

Back 41

ave length of time is 75 days (range, 40-180) in HBV infection

Front 42

Fulminant acute hepatitis

Back 42

rare form of hepatitisassociated with hepatic failure

Front 43

subclinical hepatitis withut jaundice

Back 43

persons with demonstrated antibodies but no history of hepatitis

Front 44

chronic hepatitis

Back 44

hepatic inflamation and necrosis that lasts for at least 6 months

Front 45

type A epidemiology

Back 45

fecal-oral

Front 46

type A incubation period

Back 46

15-45days

Front 47

primary hepatitis account for approx _________% of cases

Back 47

95%

Front 48

hepatitises that can result in chronic infection and possible liver cancer

Back 48

hep B and C

Front 49

Identified heps that that have been spread by unscreened blood transfusions

Back 49

hep B and C

Front 50

Hep B marker is clasical first indication of hep B infection

Back 50

HBsAg

Front 51

expected order of markers

Back 51

HBsAg, HBeAg, HBcAb, HBeAb, HBsAb

Front 52

Hep B marker used as benchmark for immunity after vaccination

Back 52

Anti-HBs

Front 53

Hep B low-level carriers have ______ in their serum

Back 53

anti-HBe

Front 54

Hep B vaccination should be administered in three doses over a span of?

Back 54

7 months

Front 55

complex DNA virus

Back 55

Hep B

Front 56

small, RNA-containing picornavirus

Back 56

Hep A

Front 57

small enveloped single stranded RNA virus

Back 57

Hep C

Front 58

long incubation Hepatitis

Back 58

Hep B

Front 59

infectios hepor short incubation hep

Back 59

Hep A