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25 Cards in this Set

  • Front
  • Back
What Cytokine promotes growth of granulocytes and macrophages; growth of dendritic cells in vitro?
GM-CSF
What Cytokine promotes granulocyte growth?
G-CSF
What Cytokine induces IFN-gamma production; enhances NK-Cell lytic activity?
IL-18
What Cytokine stimulates megakaryocyte (platelet precursor) growth?
IL-11
What Cytokine is proinflammatory, promotes neutrophil migration and differentiation, plays decisive role in autoimmunity and immune-mediated tissue damage?
IL-17
What Cytokine is Chemotactic for T-Cells; proinflammatory?
IL-16
What Cytokine is a growth factor for hematopoietic cells?
IL-3
What Cytokine promotes macrophage growth?
M-CSF
What Cytokine activates NK cells and promotes generation of TH1 CD4+ T-Cells?
IL-12
What Cytokine is a growth factor for B cells and TH2 CD4+ T cells; promotes IgE and IgG synthesis; inhibits TH1 CD4+ T-Cells?
IL-4
What Cytokine activates NK cells and macrophages; inhibits TH2 CD4+ T-Cells; induces expression of MHC class II on many cell types?
IFN-Gamma
What Cytokine produces fever; stimulates acute-phase protein synthesis; promotes proliferation of TH2 cells?
IL-1
What Cytokine is a T-Cell growth factor?
IL-2
What Cytokine is involved in inflammatory responses; activates endothelial cells and other cells of immune and nonimmune systems; induces fever and septic shock?
TNF-Alpha
What Cytokine acts on memory T-Cells to stimulate IL-17 secretion?
IL-23
What Cytokine is a growth factor for pre-T and pre-B cells?
IL-7
What Cytokine induces acute-phase protein synthesis, T-Cell activation, and IL-2 production; stimulates B-Cell Ig production and hematopoietic progenitor cell growth?
IL-6
What Cytokine is involved in the development of memory B-Cells?
IL-14
What Cytokine inhibits production of TH1 cells and macrophage function?
IL-10
What Cytokine stimulates B-Cell growth and Ig secretion; growth and differentiation factor Eosinophils?
IL-5
What Cytokine shares characteristics with IL-4 (e.g., Ig switch to IgE synthesis) but does not affect T-Cells; growth factor for human B-Cells?
IL-13
What Cytokine is involved in mast cell activation?
IL-9
What Cytokine enhances production of IgA; inhibits activation of monocyte and T-Cell subsets; active in fibroblast growth and wound healing?
TGF-Beta
What Cytokine is involved in inflammatory responses; also plays role in killing target cells by cytotoxic CD8+ T-Cells?
TNF-Beta
What Cytokine is a T-Cell growth factor; similar to IL-2?
IL-15