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25 Cards in this Set
- Front
- Back
What Cytokine promotes growth of granulocytes and macrophages; growth of dendritic cells in vitro?
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GM-CSF
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What Cytokine promotes granulocyte growth?
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G-CSF
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What Cytokine induces IFN-gamma production; enhances NK-Cell lytic activity?
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IL-18
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What Cytokine stimulates megakaryocyte (platelet precursor) growth?
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IL-11
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What Cytokine is proinflammatory, promotes neutrophil migration and differentiation, plays decisive role in autoimmunity and immune-mediated tissue damage?
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IL-17
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What Cytokine is Chemotactic for T-Cells; proinflammatory?
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IL-16
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What Cytokine is a growth factor for hematopoietic cells?
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IL-3
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What Cytokine promotes macrophage growth?
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M-CSF
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What Cytokine activates NK cells and promotes generation of TH1 CD4+ T-Cells?
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IL-12
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What Cytokine is a growth factor for B cells and TH2 CD4+ T cells; promotes IgE and IgG synthesis; inhibits TH1 CD4+ T-Cells?
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IL-4
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What Cytokine activates NK cells and macrophages; inhibits TH2 CD4+ T-Cells; induces expression of MHC class II on many cell types?
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IFN-Gamma
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What Cytokine produces fever; stimulates acute-phase protein synthesis; promotes proliferation of TH2 cells?
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IL-1
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What Cytokine is a T-Cell growth factor?
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IL-2
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What Cytokine is involved in inflammatory responses; activates endothelial cells and other cells of immune and nonimmune systems; induces fever and septic shock?
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TNF-Alpha
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What Cytokine acts on memory T-Cells to stimulate IL-17 secretion?
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IL-23
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What Cytokine is a growth factor for pre-T and pre-B cells?
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IL-7
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What Cytokine induces acute-phase protein synthesis, T-Cell activation, and IL-2 production; stimulates B-Cell Ig production and hematopoietic progenitor cell growth?
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IL-6
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What Cytokine is involved in the development of memory B-Cells?
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IL-14
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What Cytokine inhibits production of TH1 cells and macrophage function?
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IL-10
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What Cytokine stimulates B-Cell growth and Ig secretion; growth and differentiation factor Eosinophils?
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IL-5
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What Cytokine shares characteristics with IL-4 (e.g., Ig switch to IgE synthesis) but does not affect T-Cells; growth factor for human B-Cells?
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IL-13
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What Cytokine is involved in mast cell activation?
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IL-9
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What Cytokine enhances production of IgA; inhibits activation of monocyte and T-Cell subsets; active in fibroblast growth and wound healing?
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TGF-Beta
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What Cytokine is involved in inflammatory responses; also plays role in killing target cells by cytotoxic CD8+ T-Cells?
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TNF-Beta
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What Cytokine is a T-Cell growth factor; similar to IL-2?
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IL-15
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