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11 Cards in this Set
- Front
- Back
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Antigen-Presenting Cells (APC)
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Captures and displays antigens to specific lymphocytes to initiate And develop adaptive immune response.
- an. ex. dendritic cells |
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Dedritic Cells
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one of the most specialized APCs. It captures microbes, transport them to lymphoid organs and present them to naive T-cells to iniate immune response.
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Classes of Lymphocytes
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Adaptive:
-B lymphocytes (secrete antibodies) -Helper T lymphocyte (cytokines) -Cytotoxic T lymphocyte (CTL) -Regulatory T lymphocyte Innate: -Natural Killer Cells (NK) |
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Clonal selection
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Selection of cells within a population of similar cells, for cell proliferation based on the specificity of an antigen-specific cell surface receptor leading to colonal expansion
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Clone of Cells
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Selection of cells derived by mitosis from asingle ancestor cell, genetically identical among themselves and potentially distinct only by post-mitotic cellular differentiation
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Secondary Immune Response
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Reaction of lymphocytes, typically by memory cells generated suring a previous exposure to an antigen
-Usually rapid, longer |
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Primary immune response
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Reaction of naive, virgin lymphocytes during the 1st exposure to an antigen
- Stimulation of naive lymphocytes by antigens generate long-lived memory cells. |
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Naive Cells
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Individuals and lymphocytes that haave not encountered a particular antigen (immunologically inexperienced)
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Vaccination
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Intentional exposure to a non-pathogenic form of a microbe to create active protective immunity
-Active Immunization |
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Passive Immunity
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rapid protection against an antigen by transfer of cells or serum from a specifically immunized individual: does not induce an active, adaptive immune response
-Serum(antibodies) or cells (T cells) from immune animal -Adoptive transfer to naive animal *is specific but keeps NO memory |
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Active Immunity
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immune protection generated in an individual by exposure to an antigen
-the immunized indivdual plays an active role responding to the antigen *microbial antigen(vaccine or infection) *Its specifi and does keep memory |
