Immunology Cd Markers

Front 1

CD2 (LFA-2)

Back 1

secreted by: T cells, thymocytes, NK cells

function - adhesion molecule

Front 2

CD3

Back 2

secreted by: Teccls, thymocytes

function - signal transduction by TCR

Front 3

CD4

Back 3

secreted by: TH cells, thymocytes, monocytes, macrophages

function - coreceptor for TCR-MHC II, receptor for HIV

Front 4

CD8

Back 4

secreted by: CTLs, thymocytes

function - coreceptor for MHC I

Front 5

CD14 (LPS receptor)

Back 5

secreted by: moocytes, macrophages, granulocytes

function - binds LPS

Front 6

CD16

Back 6

secreted by nK cells, macrophages, neutrophils

function - opsoniation, ADCC

Front 7

CD 18

Back 7

secreted by leukocytes

function - cell adhesion

Front 8

CD 19

Back 8

expressed on B cells

function - coreceptor w./ CD21 for B cell activation

Front 9

CD 20

Back 9

expressed on B cells

function - role in B cell activation

Front 10

CD21

Back 10

found on mature B cells

function -receptor for complement C3d, complexes w/ CD19, EBV receptor

Front 11

CD28

Back 11

found on T cells

function - receptor for costimulatory B7

Front 12

CD34

Back 12

found on precursors of hematopoeitic cells, endothelial cells in HEV

function - cell cell adhesion, binds L-selectin

Front 13

CD40

Back 13

found on B cells, macrophages, dendritic cells, endothelial cells

function - binds CD40L, role in T cell dependent B cell, macrophage, dendritic cell and endothelial cell activation

Front 14

CD45

Back 14

found on hematopoietic cells

function - critical role in T and B cell antigen receptor mediated signaling

Front 15

CD56

Back 15

found on NK cells

function - not known