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18 Cards in this Set
- Front
- Back
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Professional antigen presenting cells deliver antigen to what type of cells?
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CD4+ T cells
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Professional antigen presenting cells
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Dendritic cells
Macrophages B cells |
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What type of cell is the most efficient present of antigen during a primary immune response?
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Dendritic cell
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Target cells present antigen to what type of cells?
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CD8+ T cells
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What are dendritic cells in skin epidermis called?
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Langerhan cells
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What do immature dendritic cells express in high concentration?
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FcγR
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Where does secondary immune response occur?
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At the site of infection
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Where does primary immune response occur?
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In secondary lymphoid tissues
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When are B cells the predominant antigen presenting cells?
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When antigen is limiting
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On what chromosome is MHC/HLA located on?
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Chromosome 6
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Subdivisions of class 2 MHC molecules
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DP
DQ DR |
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β2-microglobulin is encoded on what chromosome?
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Chromosome 15
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Cross presentation
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Process by which exogenous antigens normally processed in phagolysosomes and presented on the cell surface, are instead presented by Class I MHC molecules
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What type of cells is cross presentation primarily mediated by?
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Dendritic cells
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Cross priming
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Action of CD8+ T cells by cross presentation
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Disorders CMV causes in immunocompitent individuals
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Encephalitis
Pneumonia Hepatitis Retinitis Blindness |
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Determinant selection
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MHC molecules do not bind a particular peptide and so that peptide cannot be presented to T cells
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What type of cells express all members of CD1 molecules?
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Dendritic cells
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