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18 Cards in this Set

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  • Back
Professional antigen presenting cells deliver antigen to what type of cells?
CD4+ T cells
Professional antigen presenting cells
Dendritic cells
Macrophages
B cells
What type of cell is the most efficient present of antigen during a primary immune response?
Dendritic cell
Target cells present antigen to what type of cells?
CD8+ T cells
What are dendritic cells in skin epidermis called?
Langerhan cells
What do immature dendritic cells express in high concentration?
FcγR
Where does secondary immune response occur?
At the site of infection
Where does primary immune response occur?
In secondary lymphoid tissues
When are B cells the predominant antigen presenting cells?
When antigen is limiting
On what chromosome is MHC/HLA located on?
Chromosome 6
Subdivisions of class 2 MHC molecules
DP
DQ
DR
β2-microglobulin is encoded on what chromosome?
Chromosome 15
Cross presentation
Process by which exogenous antigens normally processed in phagolysosomes and presented on the cell surface, are instead presented by Class I MHC molecules
What type of cells is cross presentation primarily mediated by?
Dendritic cells
Cross priming
Action of CD8+ T cells by cross presentation
Disorders CMV causes in immunocompitent individuals
Encephalitis
Pneumonia
Hepatitis
Retinitis
Blindness
Determinant selection
MHC molecules do not bind a particular peptide and so that peptide cannot be presented to T cells
What type of cells express all members of CD1 molecules?
Dendritic cells