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15 Cards in this Set

  • Front
  • Back
which Igs have J chains?
IgM (pentamer)
IgA (dimer, tetramer)
which Igs have 4 constant domains? 3 constant domains?
IgM & IgE (4)

IgD, IgA, IgG (3)
which Igs activate complement (classical pathway)?
IgM, IgG1, IgG3
which Igs bind to macrophage Fc receptors?
IgG1, IgG3, IgE
which Igs cross the placenta?
IgG1, IgG2, IgG3
which Igs are present in secretions?
IgM (pentamer)
IgA1 and IgA2 (dimer, tetramer)
which Ig is most abundant in primary, secondary responses?
IgG (80% of serum Igs)
which Ig is the first to be released by B cells in a primary response?
IgM
which Igs are present on the surface of B cells?
IgM & IgD
which Igs induce mast cell degranulation?
IgE
(antiparasitic, allergic resp)
What is the major Ig in an adaptive secondary response?
IgG
which Ig is a marker for mature B cells?
IgD
which Ig protects musocal surfaces?
IgA
which Ig is found on mast cells and basophils?
IgE
which Igs can bind to the poly Ig receptor?
IgA (polymer) & IgM (pentamer)
must have J chain