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10 Cards in this Set

  • Front
  • Back

What antibody is produced in T independent responses?

IgM (pentamer)

T independent respond to what antigen?

Polysaccharide vaccines

In T independent responses, is there memory produced?


How long does immunity last


Which age group are vaccines not effective to?

No memory


2 years


<5 years

Secondary memory B cell responses are faster and more extensive because....

more antibody, sooner

Memory B cells reside in

Perotenial cavity,

General centers are required for what?

Long lived antibody production and nearly all B cell memory

What are centroblasts?


Where are they found?

Proliferation general center B cells


found in dark zone


undergo somatic hypermutation

What are centrocyes?


Where are they found?

General center B cells that have undergone affinity maturation


Out of cell cyucle


Found in light zone

What are follicular dendritic cells?


Where are they found?

have intact antigen in its native conformation bound to their surface


centrocytes compete to bind the antigen


Found in light zone

What are follicular T helper cells

dnflhdahd