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25 Cards in this Set
- Front
- Back
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Factors secreted by TH1 cells |
IL-2 IFN gamma |
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Factors secreted by TH2 cells |
IL-4 IL-5 IL-10 |
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Factors secreted by macrophages |
IL-1 IL-6 TNF alpha IL-8 IL-12 |
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IL-1 |
Fever, acute inflammation |
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IL-6 |
Fever, ARPs |
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IL-8 |
Major chemotactic factor for neutrophils |
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IL-12 |
Differentiation of T cells into TH1 cells Activates NK cells |
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TNF alpha |
Mediates septic shock; causes vascular leak Causes WBC recruitment |
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Function of IgG |
Complement fixation opsonization crosses the placenta to provide immunity to baby |
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Function of IgA |
Acts @ mucus membranes DOESN'T FIX COMPLEMENT Monomer in circulation Dimer when secreted requires secretory component present in breast milk |
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Which Igs fix complement |
IgM, IgG |
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Function of IgM |
Immediate immune response fixes complement Doesn't cross the placenta Monomer on B cells Pentamer when secreted |
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IgD |
Found on B cell surface |
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IgE |
Binds mast cells and basophils cross links when exposed to allergen--> T1 hypersensitivity Release of inflammatory mediators and histamine |
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IL-2 |
Stimulates T cells |
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IL-3 |
Stimulates bone marrow |
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IL-4 |
Stimulates IgE, IgG production
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IL-5 |
Stimulates IgA production and eosinophils |
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Cell surface proteins on all T cells |
TCR CD3 CD28 |
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Cell surface proteins on helper T cells |
CD4, CD40L |
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Cell surface proteins Tregs |
CD4, CD25 |
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Cell surface proteins on B cells |
IgM, IgD CD19, CD20, CD21 CD40 MHC I MHC II B7 |
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Cell surface proteins on Macrophages |
CD 14 CD40 MHC II B7 Fc, C3b receptors |
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Cell surface proteins on NK cells |
CD16 (binds Fc of IgG) CD56 |
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Hematopoietic stem cells |
CD34 |
