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33 Cards in this Set
- Front
- Back
autoantibodies in SLE
|
ANA
dsDNA***definitive Smith histone (drug induced, procainamide and hydralazine) |
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autoantibodies in RA
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IgM forms anti-IgG
|
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autoantibodies in scleroderma
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centromere (CREST)
scl-70 (diffuse) |
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autoantibodies in primary biliary cirrhosis
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mitochondrial
|
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autoantibodies in celiac's
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gliadin
|
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autoantibodies in goodpasture's
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basement membrane (type 4 collagen)
|
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autoantibodies in pemphigus vulgaris
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epithelial cell
|
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autoantibodies in hashimoto's thyroiditis
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microsomal, thyroglobulin
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autoantibodies in Grave's
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thyrotropin
|
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autoantibodies in polymyositis and dermatomyositis
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jo-1
|
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autoantibodies in Sjogren's
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SS-A (ro)
SS-B (la) |
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autoantibodies in mixed connective tissue disease
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U1 RNP ribonucleoprotein
|
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autoantibodies in autoimmune hepatitis
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smooth muscle
|
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autoantibodies in DM 1
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glutamate decarboxylase
|
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autoantibodies in wegener's
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C-ANCA
|
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autoantibodies in polyarteritis nodosum
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p-ANCA
|
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HLA subtypes of RA
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DR4
|
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diseases with B27 HLA subtypes
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psoriasis
ankylosiing spondylitis IBD Reiter's |
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diseases with B8 HLA subtypes
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Grave's
Celiac's |
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diseases with DR2 HLA subtypes
|
MS
hay fever SLE Goodpasture |
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diseases with DR3 HLA subtypes
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DM1
SLE |
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diseases with DR4 HLA subtypes
|
RA
DM1 |
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diseases with DR5 HLA subtypes
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pernicious anemia
hashimoto's |
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diseases with DR7 HLA subtypes
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steroid responsive nephrotic syndrome
|
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examples of type 4 hypersensitivity
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DM1
MS Guillain Barre Hashimot's GVHD PPD Contact dermatitis |
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examples of Type 3 hypersensitivity
|
SLE
RA polyarteritis post-strep glomerulonephritis serum sickness arthus reaction hypersensitivity pneumonitis |
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examples of type 2 hypersensitivity
|
hemolytic anemia
ITP erythroblastosis fetalis rheumatic fever good pastures bullous pemphigoid grave's MG |
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mechanism of RA autoimmunity
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B cells stimulate IgM, IgG and IgA to the Fc region of IgG
Type 3 |
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Mechanism of autoimmunity in Grave's Disease
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TSH receptor TH2 of CD4
|
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mechanism of autoimmune hemolytic anemia
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IgG or IgM to RBCs
|
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mechanism of autoimmunity in MS
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CD4 TH1 and IFN G to myelin sheath
|
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mechanism of autoimmunity in SLE
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IgG against cell surface
|
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mechanism of Hashimoto's
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CD4 TH1 lymphocytic infiltrate to thyroglobulin
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