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23 Cards in this Set
- Front
- Back
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what are the three of component of a lymph node?
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follicle, paracortex, medulla
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structure of lymph node
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encapsulated with trabeculae. many afferents, 1+ efferent
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what are three function of lymph node?
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ns filtration by macrophage, storage/activation of B/T cells, antibody production
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what is the function of follicle?
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B-cell localization and proliferation; 1 follicle: dense, dormant B cell; 2 follicle: pale central germinal cell, active
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what is the structure of the medulla?
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medullary cords and medullary sinus
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what does the medullary cords consist of?
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closely packed lymphocytes and plasma cells
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what is the function of the medullary sinus?
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communicate with efferent lymphatics and contains reticular cells and macrophages
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what is the function of the paracortex (located btwn follicles and medulla)?
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contains HEV where T/B cells enter from blood; houses T cells
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what happens to the paracortex in an extreme cellular immune response?
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paracortex enlarges
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in what syndrome is the paracortex not well developed?
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DiGeorge syndrome (22q11 deletion)
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what is the lymphatic drainage of...
upper limb, lateral breast? |
axillary
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what is the lymphatic drainage of...stomach?
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celiac
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what is the lymphatic drainage of...duodenum, jejunum
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superior mesenteric
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what is the lymphatic drainage of...sigmoid colon
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colic --> inferior mesenteric
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what is the lymphatic drainage of...rectum (above pectinate line)
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superfical inguinal peinteral iliac
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what is the lymphatic drainage of...anal canal (below pectinate line)
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superfical inguinal
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what is the lymphatic drainage of...testes
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superfical/deep plexus --> para-aortic
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what is the lymphatic drainage of...scrotum
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superfical inguinal
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what is the lymphatic drainage of...superficial thigh
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superficial inguinal
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what is the lymphatic drainage of...lateral side of dorsum of foot
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popliteal
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what does the right lymphatic duct drain?
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right arm, right half of head
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what does the thoracic duct drain?
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everything else except right arm, right half of head.
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what is structure of sinusoid of spleen?
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long vascular channel in red pulp with fenestrated barrel hoop BM; contains macrophages
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