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16 Cards in this Set
- Front
- Back
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Generally, what cell type gives rise to the cells of Innate Immunity?
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Common Myloid Progenitor
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Generally, what cell type gives rise to the cells of Adaptive Immunity?
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Common Lymphoid Progenitor
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What are the two types of lymphoid organs?
Examples of Both? |
- Primary and Secondary Lymphoid Organs
Primary = Bone Marrow and Thymus Secondary = Lymphnodes, Spleen, Peyers Patch, Tonsils, etc |
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Where does the antigen Independent stage of B Cell Development occur?
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Bone Marrow
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Where does the Antigen Dependent stage of B Cell Development occur?
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Lymphnodes
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What are the two main divisions in the Thymus?
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1. Cortex
2. Medulla |
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In which direction do T Cells migrate in the Thymus as part of their primary education?
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Cortex to Medulla to eliminate self reactive T Cells
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What are the two types of Follicles seen in a lymphnode?
Main differences between them? |
Primary and Secondary
Primary = Has not seen Antigen, No Germinal Center Secondary = Has seen Antigen, Does have Germinal Center |
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In which follicle type is somatic hypermutation and class switching seen in the lymphnode?
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Secondary Follicle
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What are the 3 zones within a Follicle?
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1. Mantle Zone
2. Germinal Center 3. Marginal Zone |
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Through which structure do lymphocytes return to the blood from the lymphatics?
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Thoracic Duct
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What doe MALT stand for, what is it?
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- Mucosa Associated Lymphoid Tissue
- 3rd arm of secondary lymphoid tissue, mostly in respiratory and GI tracts ex. Peyer's patches |
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What are the functions/characteristics of a neutrophil?
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1. Most important component in killing Bacteria and Fungi
2. Quite Large, most abundant WBC 3. Lobed Nucleus |
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What are the functions/characteristics of a monocyte?
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- Largest cell found in peripheral blood
- Functions in phagocytosis - Migrates to tissues to do job ex: osteoclasts, alveolar macrophages |
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What are the functions/characteristics of a Eosinophils?
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- Not well understood
- Perhaps play a role in worm infections and allergies |
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What are the functions/characteristics of a Basophils?
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- Very important in hypersensitivity / allergic reactions
- inflammatory response to parasites |
