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30 Cards in this Set
- Front
- Back
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a substance that induces an immune response |
antigen |
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secreted forms of immunoglobulin made by B cells and plasma cells |
antibody |
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the collection of different antibody molecules in an individual |
antibody repertoire |
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generalized wasting syndrome associated with chronic disease |
cachexia |
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substance that induced cachexia |
cachectin |
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small proteins involved in attracting cells to sites of infection of inflammation |
chemokines |
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soluble or cell membrane bound proteins produced by cells that interact with receptors on the same cell or on different cells |
cytokines |
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a portion of an antigenic molecule that is bound by an antibody or is bound in an MHC peptide binding groove and recognized by a T cell receptor |
epitope |
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structure that occurs at a site of chronic inflammation in response to a persistent stimulus, comprised of macrophages, surrounded by T cells |
granuloma |
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common progenitor of all cells of the blood |
Hematopoietic stem cell |
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term to identify antibodies if the specificity for antigen is unknown |
immunoglobulins |
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family of molecules that are structurally similar to immunoglobulins |
immunoglobulin superfamily |
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molecules on the cell membranes that are involved in binding to vascular endothelial cells; promote tight binding prior to cell migration out of the blood and into the tissues |
integrins |
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proteins produced by cells that interact with receptors on the same cell or on different cells |
interleukin |
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a tumor of an antibody forming plasma cell |
myeloma |
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antibody and complement components that bind to antigens and facilitate their phagocytosis by neutrophils or macrophages |
opsonin |
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receptor present on the basal side of epithelial cells that binds polymeric immunoglobulins (dimeric IgA or pentameric IgM) and transports these immunoglobulins across epithelial cells |
poly-Ig receptor |
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a large, multi-subunit molecular complex present in cytoplasm that degrades cytoplasmic proteins into peptides for transport into the endoplasmic reticulum |
proteasome |
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organs or tissues in which lymphoid precursor cells mature into lymphocytes that express antigen-specific receptors. the cell subsequently binds and responds to antigens |
primary lymphoid organs/tissues |
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organs or tissues in which immune responses take place |
secondary lymphoid organs/tissues |
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Fab |
fragment of antigen binding |
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Fc |
fragment crystylizable |
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ICAM |
intercellular adhesion molecule |
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LFA |
lymphocyte function associated antigen |
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LPS |
lipopolysaccharide |
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MHC |
major histocompatibility complex |
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PAMP |
pathogen associated mulecular patterns |
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RAG |
recombination activating genes |
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TCR |
T cell receptor (for antigen) |
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3 cytokines |
TNF-alpha
IL-1 IL-6 |
