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33 Cards in this Set
- Front
- Back
Polyspecific antihuman globulin contains
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anti-IgG and anti-C3d
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Rouleaux is a false-positive reaction that would likely be observed during which tests?
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Weak D test
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A person whose red cells type as M+N+ with antisera would be
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a heterozygote
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Could parents who are both phenotyped as group A have a group O child?
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yes
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If anti-M was reacted with red cells that are M+N+, how would they compare with red cells that are M+N?
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Weaker
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What type of inheritance pattern does a father that carries the Xga blood group trait and passes it on to all of his daughters but to none of his sons demonstrates?
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X-linked dominant
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Which marker that is used for paternity test provides the most useful statistical value?
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Human Leukocyte antigen typing
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Mitosis results in how many chromosomes?
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two cells with the same number of chromosomes as the original
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When does crossing over occur?
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Meiosis
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When an individual is said to be group A, it refers to the individual's:
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Phenotype
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What is an advantage of Nucleic Acid Testing (NAT) for viral marker testing?
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A small amount of DNA or RNA can be detected
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Autosomal means
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A trait that is not carried on the sex chromosomes
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What must be true when using the Hardy-Weinberg equation to calculate genetic frequencies?
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The population statistics must be large, mutation, mating must be random
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If two traits were found to occur higher in a population together than each occurs separately, they may be linked
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The genes are close together on the same chromosome
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What is the approximate probability of finding a compatible unit of blood for a Dpositive patient with antibodies to C, E, and K, if the frequency of C is 70%, E, 30%, and K
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2 out of 10
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Most blood group systems are inherited as
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Autosomal Codominant
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The linked HLA genes on each chromosome are inherited as
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Haplotype
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How are the short pieces of single-stranded DNA in the PCR reaction that are complementary and mark the sequence to be amplified called?
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Primers
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Hematopoietic progenitor cell engraftment evaluation following a transplant evaluates which specific markers in the recipient
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Similarities and differences of short tandem repeats of DNA
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Which ABO phenotype selection contains the most H antigen and the least H antigen, respectively, on the red cell's surface?
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O, A(1)B
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How is the test procedure that combines patient's serum with commercial Al and B reagent red cells called?
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ABO reverse grouping
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The appropriate strategy if the results of red cell and serum testing in the ABO typing procedure have negative agglutination reactions is |
Incubate tubes at room temperature or 4 degrees C with an auto control |
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The agglutination reaction of red cells from a Bombay phenotype with anti-H lectin would be
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Negative
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Which situation is most likely to cause intravascular hemolysis when an incompatible transfusion is given? |
Group B packed cells to a group O recipient |
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What is the most likely discrepancy on a blood sample from a 90-year-old man that was submitted to the blood bank for a type and screen before surgery. The forward type demonstrates as a group A, whereas the reverse type appears to be group AB.
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That the patient has low-titer isoagglutinins
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Most "naturally occurring" ABO system antibodies fall into class
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IgM
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What substances are found in the saliva of a group A person who also inherited the secretor gene?
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A, H
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What percentage of the group A population are type A2?
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20%
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What is the percentage of individuals who demonstrate H in their saliva?
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80%
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Which reagent is used to distinguish between an Al and A2 blood type?
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Dolichos biflorus lectin
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What is the subgroup of A with the least amount of A antigen?
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Ael
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Why is it sometimes necessary to distinguish Al and A2 blood types?
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To resolve a discrepancy between the forward and reverse typing
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The immunodominant sugar that corresponds to Group A is
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N-acetylgalactosamine
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