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33 Cards in this Set

  • Front
  • Back
Polyspecific antihuman globulin contains
anti-IgG and anti-C3d
Rouleaux is a false-positive reaction that would likely be observed during which tests?
Weak D test
A person whose red cells type as M+N+ with antisera would be
a heterozygote
Could parents who are both phenotyped as group A have a group O child?
yes
If anti-M was reacted with red cells that are M+N+, how would they compare with red cells that are M+N?
Weaker
What type of inheritance pattern does a father that carries the Xga blood group trait and passes it on to all of his daughters but to none of his sons demonstrates?
X-linked dominant
Which marker that is used for paternity test provides the most useful statistical value?
Human Leukocyte antigen typing
Mitosis results in how many chromosomes?
two cells with the same number of chromosomes as the original
When does crossing over occur?
Meiosis
When an individual is said to be group A, it refers to the individual's:
Phenotype
What is an advantage of Nucleic Acid Testing (NAT) for viral marker testing?
A small amount of DNA or RNA can be detected
Autosomal means
A trait that is not carried on the sex chromosomes
What must be true when using the Hardy-Weinberg equation to calculate genetic frequencies?
The population statistics must be large, mutation, mating must be random
If two traits were found to occur higher in a population together than each occurs separately, they may be linked
The genes are close together on the same chromosome
What is the approximate probability of finding a compatible unit of blood for a Dpositive patient with antibodies to C, E, and K, if the frequency of C is 70%, E, 30%, and K
2 out of 10
Most blood group systems are inherited as
Autosomal Codominant
The linked HLA genes on each chromosome are inherited as
Haplotype
How are the short pieces of single-stranded DNA in the PCR reaction that are complementary and mark the sequence to be amplified called?
Primers
Hematopoietic progenitor cell engraftment evaluation following a transplant evaluates which specific markers in the recipient
Similarities and differences of short tandem repeats of DNA
Which ABO phenotype selection contains the most H antigen and the least H antigen, respectively, on the red cell's surface?
O, A(1)B
How is the test procedure that combines patient's serum with commercial Al and B reagent red cells called?
ABO reverse grouping

The appropriate strategy if the results of red cell and serum testing in the ABO typing procedure have negative agglutination reactions is

Incubate tubes at room temperature or 4 degrees C with an auto control

The agglutination reaction of red cells from a Bombay phenotype with anti-H lectin would be
Negative

Which situation is most likely to cause intravascular hemolysis when an incompatible transfusion is given?

Group B packed cells to a group O recipient

What is the most likely discrepancy on a blood sample from a 90-year-old man that was submitted to the blood bank for a type and screen before surgery. The forward type demonstrates as a group A, whereas the reverse type appears to be group AB.
That the patient has low-titer isoagglutinins
Most "naturally occurring" ABO system antibodies fall into class
IgM
What substances are found in the saliva of a group A person who also inherited the secretor gene?
A, H
What percentage of the group A population are type A2?
20%
What is the percentage of individuals who demonstrate H in their saliva?
80%
Which reagent is used to distinguish between an Al and A2 blood type?
Dolichos biflorus lectin
What is the subgroup of A with the least amount of A antigen?
Ael
Why is it sometimes necessary to distinguish Al and A2 blood types?
To resolve a discrepancy between the forward and reverse typing
The immunodominant sugar that corresponds to Group A is
N-acetylgalactosamine