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5 Cards in this Set
- Front
- Back
Where found? Action? Other qualities? |
Found: Blood & lymph Action: causes agglutination/precipitation of antigen, neutralises toxins, immobilises bacteria, neutralises viruses & activates complement system. Other qualities: longest half-life, promotes phagocytosis, only Ig able to cross placenta |
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Found? Action? Other qualities? |
Found: surface of B cells Action: acts as receptor for antigen, eliminates self-reactive B cells Other qualities: co-expressed with IgM, present in serum - low amounts |
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Found? Action? Other qualities? |
Found: Mast cells, Basophils Action: Defends against worm infections by causing release of enzymes from eosinophils, main host defence against worms. Other qualities: Mediates immediate hypersensitivity by coursing release of mediators from mast cells & basophils upon exposure to antigen, doesn't fix complement |
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Found? Action? Other qualities? |
Found: serum & secretions Action: prevents attachment of bacteria & viruses to mucous membrane, primary defence against local response to GI infections -> prevents epithelial attachment Other qualities: major Ig in external secretions, serum=monomer, secretion=dimer, possesses antibacterial activity, efficient antiviral Ab, efficient agglutinating Ab. |
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Found? Action? Other qualities? |
Found: in blood antigen receptor on B cell surface (blood) Action: primary response to antigen, most efficient at activating complement system (activated while in blood) Other qualities: 1st Ig produced in immune response, doesn't cross placenta, exists as pentameric molecule |
