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20 Cards in this Set
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- 3rd side (hint)
Immunology tests for fungal infections
How many types of tests there are? |
3
List |
Tests for fungal Abs and Ags Skin tests |
|
Immunology tests for fungal infections
3 List |
Tests for fungal Abs Tests for fungal Ags Skin tests |
|
|
Immunology tests for Fungal infections
_____________ Tests for fungal Ags Skin tests |
Tests for fungal abs
Results that indicate fungal infections
|
Negative to positive 3 fold rise in Ab titer Single high titer |
|
Immunology tests for fungal infections
Tests for fungal Abs ________________ Skin tests |
Tests for fungal Ags
Example |
Cryptococcal Ag |
|
Immunology tests for fungal infections
Tests for fungal Ags Example |
Cryptococcal Ag
Test? |
Latex agglutination |
|
Test for Cryptococcal Ag by latex agglutination
Procedure |
Pt. sample + Latex beads
Mix, rotate
Look for agglutination |
|
|
Test for cryptococcal Ag by latex agglutination
Procedure
________+Latex beads
Mix, rotate
Look for agglutination |
Pt. sample
List |
CSF serum |
|
Test for cryptococcal Ag by latex agglutination
Procedure
Pt. sample + __________
Mix, rotate
Look for agglutination |
Latex beads
Description |
Coated with Anti-Cryptococcus Ab |
|
Test for cryptococcal Ag by latex agglutination
Procedure
Pt. sample + Latex agglutination
Mix and rotate
Look for _______ |
Agglutination
Interpretation of results |
+ Agglutination = + Ag = Presence of Cryptococcal infection |
|
Test for cryptococcal Ag by latex agglutination
+ Agglutination |
+ Ag = ? |
Presence of Cryptococcal infection |
|
Fungal
Skin test results List |
Positive Negative Positive to negative Negative to positive |
|
|
Fungal skin tests
How many possible results there are? |
4
List |
Positive Negative Positive to negative Negative to positive |
|
Fungal skin tests
________ negative Positive to negative Negative to positive |
Positive
Meaning |
Exposure to fungus
Good prognostic sign: development of cell-mediated immunity |
|
Fungal skin tests
Positive __________ Positive to negative Negative to positive |
Negative
Meaning |
No exposure to fungus
|
|
Fungal skin test
Positive Negative _____________ Negative to positive |
Positive to negative
Meaning |
Poor prognostic sign: Immunosuppression |
|
Fungal skin test
Positive Negative Positive to negative _______________ |
Negative to positive
Meaning |
Current infection |
|
Serologic testing Advantages over microbiology testing
How many? |
5
List |
Serologic testings
- more rapid results - more sensitive than culture
- Culture is difficult/impossible for some organism
- Only means of detecting past infections
- Monitor the course of disease over time |
|
Serologic testing
5 advantages over microbiology testing |
Serologic testings
- faster than - more sensitive than culture methods
Culture of some organisms are difficult/impossible
Only means of detecting past infection
Can monitor the course of disease over time (Description) |
inc Ab titer: active infection dec Ab titer: recovery |
|
Limitations/Disadvantages of serologic testings |
Not definitive b/c? |
Possibility of false positive false negative |
|
Limitations/Disadvantages of serologic testings
Not definitive b/c |
Possibility of false positive or negative results |
|