Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
29 Cards in this Set
- Front
- Back
|
ABO system
|
blood group polysaccharide antigens
|
|
|
affinity
|
the force btn molecules that impels them to bind to one another non-covalently
|
|
|
allotype
|
antigenic differences w/in a give class of Ig btn members of the same species
|
|
|
allotypic
|
pertaining to an allotype
|
|
|
Am
|
the IgA allotypes
|
|
|
anti-idiotypic antibodies
|
antibodies that are specific for a set of idiotopes
|
|
|
avidity
|
sum of the affinities when two molecules are interacting (assuming one molecule has more than one binding site)
|
|
|
class of antibody
|
antibody isotypes
|
|
|
CDR
complementary determining region |
the part of the variable region that is hypervariable btn antibodies
|
|
|
constant region
|
the part of antibodies that is the same for all antibodies of one class w/in an isotype
|
|
|
crossreactive
|
refers to the fact that some antibodies will bind to antigens that are closely related
|
|
|
Gm
|
the IgG allotypes
|
|
|
half-life
|
period during which the number of molecules is decreased by 50%
|
|
|
HAMA
human anti-mouse antibodies |
human responses to mouse antibodies injected for therapeutic value
|
|
|
hybridoma
|
cell created from fusion of a tumor cell and a normal cell
|
|
|
idiotope
|
one component w/in the antibody hypervariable region that is unique
|
|
|
idiotype
|
sum of the idiotopes
|
|
|
isohemagglutinin
|
IgM antibodies specific for A and/or B antigens on RBCs
|
|
|
J chain
|
the joining chains of IgM and IgA antibodies
|
|
|
kappa
|
one of two light chain antibody constant regions
|
|
|
Km
|
the kappa chain allotypes
|
|
|
lambda
|
one of two light chain antibody constant regions
|
|
|
papain
|
enzyme that cleaves the IgG antibody above the inter-heavychain disulfide bond, yielding 3 parts: 2 copies of a single antigen-binding region (2 F(ab)) and 1 Fc that cannot bind antigen
|
|
|
pepsin
|
enzyme that cleaves the IgG antibody below the inter-heavychain disulfide bond, yielding 3 parts: 1 molecule with a two-antigen-binding region (Fab2) and 2 Fc fragments
|
|
|
proteolysis
|
protein cleavage by enzymes
|
|
|
reaginic
|
related to allergies and IgE antibodies
|
|
|
secretory component
|
a protein present on the basolateral face of the lumenal epithelial cell that binds to dimeric IgA, allowing endocytosis and transport of IgA into the lumen; part of the secretory component breaks off and stays attached to IgA; this released IgA is called secretory IgA
|
|
|
subclass
|
further division of antibody classes (e.g. IgG further divided into IgG1, IgG2, IgG3, IgG4)
|
|
|
variable region
|
region of antibodies that varies from one antibody to another even w/in one class
|
