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4 Cards in this Set
- Front
- Back
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What is the signal for macrophages to stop resting and start expressing MHCII (Become an APC?)
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interferon gamma, mainly produced by helper T cells and NK cells
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What do hyperactivated macrophages (ie, those that have contacted LPS or mannose) secrete?
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TNF: cytokine that can kill tumor cells and virus-infected cells and activate other immune components
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What are the 'alarm cytokines' given off by macrophages?
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IL-1 and TNF
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A macrophage produces lots of ____, and gets primed by _____.
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produces TNF, gets primed by IFN-gamma (produced by NK cells)
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