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53 Cards in this Set
- Front
- Back
what medications cause anticholinergic side effects
|
low potency neuroleptics
-thioridazine -chlorpromazine TCA 1st Gen antihistamine amantadine |
|
what initiates VDJ rearrangement
|
RAG 1 and 2
|
|
what does RAG recognize
|
RSS on the flank of V D and J coding regions
|
|
which organelle is important in pasma cells
|
RER
GA |
|
cytokine:
promotes B cell |
4
5 |
|
cytokine:
produced by Th1 |
2
IFN y |
|
cytokine:
produced by Th2 |
4
5 10 |
|
cytokine:
activates eosinophils |
5
|
|
cytokine:
activates macrophages |
IFN y
|
|
cytokine:
inhibits macrophages |
10
|
|
cytokine:
is a pyogene secreted by monocytes and macrophages |
1
6 TNFa |
|
cytokine:
inhibits Th1 |
10
|
|
cytokine:
inhibits Th2 |
IFN y
|
|
cytokine:
mediates inflammation |
1
6 TNFa |
|
cytokine:
enhances IgG and E |
4
|
|
cytokine:
enhances IgA |
5
|
|
cytokine:
released by virally infected cells |
IFN a and B
|
|
cytokine:
Bonemarrow |
3
|
|
cytokine:
t cells |
2
|
|
antibodies to TNF a
|
adaminumab
etanercept infliximab |
|
Immunosuppressant:
precursor to 6MP |
azathioprine
|
|
Immunosuppressant:
nephrotoxicity preventable with mannitol |
cyclosporine
|
|
Immunosuppressant:
Ab that binds CD 3 |
muromunab
|
|
Immunosuppressant:
Ab to IL 2 |
daclizumab
|
|
Immunosuppressant:
inhibits IMP dehydrogenase |
mycophenolate
|
|
Immunosuppressant:
inhibits calcuneurin decreasing IL2 |
cyclosporine
|
|
Immunosuppressant:
binds FKBP inhibiting IL 2 |
ticolimus
|
|
Immunosuppressant:
binds FKBP-12 which inhibits mTOR |
sirolimus
|
|
Immunosuppressant:
for lupus nephritis |
cyclosporine
azathioprine mycophenolate |
|
Immunosuppressant:
metabolized by XO |
azathioprine
|
|
deficiency of this Ig can cause recurrent Giardiasis
|
IgA
|
|
what preformed antibodies can be given after exposure
|
tetanus
botulinum HBV Rabies RSV |
|
what are the live attenuated vaccines
|
smallpox
yellow fever chicken pox sabins polio MMR |
|
what are the killed vaccines
|
rabies
influenza salk polio HAV |
|
what are the recombinant vaccines
|
HBV
HPV |
|
what is the only live attenuated vaccine that can be given to immunocompromised
|
MMR
|
|
what are the egg based vaccines
|
Flu
yellow fever MMR (very little) |
|
Amyloid:
senile cardiac |
transthyretin
|
|
Amyloid:
DM2 |
amylin
|
|
Amyloid:
medullary thyroid carcinoma |
A-CAL
|
|
Amyloid:
alzheimers |
B-amyloid
|
|
Amyloid:
dialysis |
B2-microglobulin
|
|
Amyloid:
multiple myeloma |
AL
|
|
Amyloid:
chronic diseases |
AA
|
|
Cytokine:
activates endothelium to express adhesion molecules |
IL 1
|
|
Cytokine:
stimulates production of acute phase proteins |
IL 6
|
|
Cytokine:
activates NK cells |
IL 12
|
|
Cytokine:
functions like GM-CSF |
IL 3
|
|
Cytokine:
induces differentiations into Th2 cells |
IL 4
|
|
Cytokine:
decreases inflammatory response |
IL 10
|
|
Therapeutic Ab:
CD 20 |
Rituximab
|
|
Therapeutic Ab:
IgE |
omalizumab
|
|
Therapeutic Ab:
erb B2 (HER 2 cancers) |
trastuzumab
|