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68 Cards in this Set
- Front
- Back
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ANA antibodies
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SLE
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Anti-dsDNA (anti-smith)
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Speicific for SLE
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Antihistone antibodies
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Drug induced lubus
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Anti-IgG (rheumatoid factor
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Rheumatoid arthritis
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Anticentromere antibodies
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Scleroderma (crest)
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Anti-Scl-70 (Anti-DNA-topoisomerase I)
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Scleroderma (diffuse)
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Antimitochondrial antibodies
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primary biliary cirrhosis
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Antigliadin, antiendomysial
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celiac disease
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Anti-basement membrane antibodies
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Goodpastures
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Anti-desmoglein
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Pemphigus vulgaris
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Antimicrosomal, antithyroglobulin
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Hashimoto's thyroiditis
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Anti-Jo-1
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Polymyositis, dermatomyositis
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Anti-SS-A, SS-B
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Sjogrens syndrome
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Anti-U1 RNP ribonucleoprotein
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Mixed connective tissue disease
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Anti-smooth muscle
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Autoimmune hepatitis
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Anti-glutamate Decarboxylase
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Type 1 diabetes mellitus
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c-ANCA
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Wegeners granulomatosis
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p-ANCA
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Other vasculaities
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What hypersensitivity reaction is Anaphylaxis
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Type 1
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What hypersensitivity reaction is Bee sting
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type 1
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What hypersensitivity reaction is food and drug allergies
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type 1
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What hypersensitivity reaction is hives and asthma
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type 1
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What hypersensitivity reaction is hay fever, eczema
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type 1
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What hypersensitivity reaction is hemolytic anemia
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type II
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What hypersensitivity reaction is pernicious anemia
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type II
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What hypersensitivity reaction is erythroblastosis fetalis
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type II
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What hypersensitivity reaction is Acute hemolytic transfusion reactions
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Type II
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What hypersensitivity reaction is Rheumatic fever
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type II
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What hypersensitivity reaction is Goodpastures syndrome
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Type II
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What hypersensitivity reaction is Bullous pemphigoid
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Type II
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What hypersensitivity reaction is Pemphigus vulgaris
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Type II
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What hypersensitivity reaction is Graves disease
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Type II
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What hypersensitivity reaction is Myasthenia gravis
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Type II
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What hypersensitivity reaction is SLE
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Type III
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What hypersensitivity reaction is Rheumatoid arthritis
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Type III
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What hypersensitivity reaction is Polyarteritis nodosa
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Type III
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What hypersensitivity reaction is Poststreptococcal glomerulonephritis
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Type III
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What hypersensitivity reaction is Serum Sickness
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Type III
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What hypersensitivity reaction is Farmers lung
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Type III
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What hypersensitivity reaction is Multiple sclerosis
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Type IV
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What hypersensitivity reaction is Guillain-Barre syndrome
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Type IV
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What hypersensitivity reaction is Hashimotos thyroiditis
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Type IV
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What hypersensitivity reaction is Graft vs host disease
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Type IV
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What hypersensitivity reaction is PPD for TB
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Type IV
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What hypersensitivity reaction is Contact dermatitis (poison ivy, nickle)
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Type IV
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What Does IL-1 Do
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Fever
**recruit leukocytes** |
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What does IL-2 do
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Stimulates growth of helper and cytotoxic T-Cells
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What does IL-3 Do
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Secreted by activated T-cells
**Stims Growth of Bone Marrow stem cells** |
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What does IL-4 Do
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Secreted by Th2 cells
Promotes growth of of B cells **isotype switch IgE and IgG |
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What does IL-5 Do
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Secreted by Th2 CElls
Promotes differentiation of B cells Isotype switching to IgA ***also activation of Eosinophils*** |
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What does IL-6 do
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Stims acute phase reactants and immunoglobulins
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What does IL-8 do
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major chemotactic factor for neutrophils
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What does IL-10 do
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Only inhibitory factor that inhibits Th1 and activates Th2
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What does IL-12 do
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Secreted by B cells and macrophages
**activates NK and Th1 Cells** |
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What does Gamma Interferron do
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Secreted by Th1 cells
Stims macrophages **activates Th1, inhibits Th2** |
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What does TNF do
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secreted by Macrophages
Mediates septic shock causes leukocyte recruitment/vascular leak |
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What is the disease that is X-linked recessive. progressive deletion of B and T cells.
and Has a trial of thrombocytopenic purpura, infections, and eczema |
Wiskott-Aldrich syndrome
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What disease has a defect in DNA repair enzymes and presents with cerebellar defects, spider angiomas, and IgA deficiency
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Ataxia-Telangiectasia
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What disease has a defect in CD18 proten on phagocytes and presents with recurrent bacterial infections, absent pus formation, and delayed separation of umbilicus
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Leukocyte adhesion deficiency
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What disease is a Autosomal Recessive defect in microtubular function with decrease phagocytosis that presents wth recurrent pyogenic infections by Staph, Strep, partial albinism, peripheral neuropathy?
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Chediak-Hegashi syndrome
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What does Th1 secrete
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INF-G, IL-2
They are the ATTACK T-CELLS INF-G = activate macrophages IL-2 Stim Cytotoxic T-Cells |
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What does Th2 secrete
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IL-4, 5, 6, and 10
These all cause Ig Isotype switch 10 activates Th2 and inhibits Th1 |
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CD 19, CD20, CD21 are all markers for what cell type
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B cells
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CD56 is found on what cell
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NK cells
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What is a synergenic graft
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Graft between identical twins
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What is a allograft
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tissue from same species
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What is a autograft
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Tissue from the same person
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what cell has CD14
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macrophages
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