Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
30 Cards in this Set
- Front
- Back
|
What three functions do your immunity serve
|
Defense
Homeostasis Surveillance |
|
|
Immunity where antibodies or T-cells are produced after either a natural exposure to an antigen or after immunization
|
Active Immunity
|
|
|
Immunity with performed antibodies or T-lymphocytes that are transferred from a donor to a recipient
|
Passive Immunity
|
|
|
Foreign Molecules that induce specific immune responses
|
Antigens
|
|
|
What are the central lymphoid organs
|
Thymus Gland
Bone Marrow |
|
|
What is the thymus gland important in?
|
Differentiation and maturation of T-lymphocytes
|
|
|
What does bone marrow do?
|
Produces RBC, WBC, and Platelets
Origin of stem cells of T & B Cell precursors |
|
|
Peripheral lymphoid organs
|
Tonsils
Small Intestine Skin Lymph Nodes Spleen |
|
|
What are the plasma cells in B cells for
|
Making Immunoglobulin
Memory Cells |
|
|
What are Cytolytic T Cells (CD8+ Cells)) for
|
They attack and kill target cells
|
|
|
What are the Helper T-Lymphocytes (CD4+ Cells) for?
|
Antibody production by B Cells
Promote delayed-type hypersensitivity (DTH) Activation of cytolytic T Cells |
|
|
Cells that are found in the skin as Langerhans that are tree shaped
|
Dendritic Cells
|
|
|
What are the functions of the dendritic cells
|
Capture antigen and take it to T cells to kill antigen presenting cells
|
|
|
What do mast cells and basophils do?
|
Mediate immediate hypersensitivity reactions
|
|
|
What do neutrophils (polymorphonuclear leukocytes) do?
|
Phagocytize bacteria and other foreign particles
|
|
|
What do Esoinophils do?
|
Attack and destroy foreign particles that have been coated with antibodies of the IgE class
|
|
|
Where do lymphocytes come from?
|
Stem cells in the bone marrow or fetal liver
B Cells mature in the bone marrow T Cells mature in the thymus They move to the lymph nodes to wait for an antigen-presenting cell to activate them |
|
|
What are B cells also known as in the Humoral Immune Response?
|
Bursal Equivalent Tissue
|
|
|
What do the plasma b cells produce in the humoral immune response
|
5 types of antibodies and immunoglobulins
|
|
|
How is a B Cell activated?
|
An Antigen-presenting cell activates a Th cell, which goes to activate the B cell
|
|
|
What is the difference between the plasma and memory cells of the B cells
|
memory stay in the body for a re-exposure while plasma cells create antibodies
|
|
|
What are the functions of antibodies
|
Neutralize bacteria
Neutralize Viruses Opsonize Bacteria Activate Components of AIR |
|
|
Where is the IgA antibody found?
|
Saliva
Sweat Tears Mucus Breast Milk Colostrum Lining of mucous membranes |
|
|
Where is the IgD antibody found?
|
surface of developing B-lymphocytes
|
|
|
What is the function of IgD
|
Acts as an antigen receptor for B Cells
|
|
|
Characteristics of IgE antibody?
|
Least concentrated immunoglobulin
Mediator of many common allergic reponses Defender against parasites Attaches to mast cells and basophils found in plasma and IF |
|
|
Characteristics of IgG antibody?
|
Most abundant class (80-85%)
Found in plasma and IF Enhances phagocytosis Transported across the placenta |
|
|
Characteristics of IgM antibody?
|
Can't cross placenta
responsible for primary immune response Fixes complement to promote lysis Receptor for antigen recognition Forms antibodies to ABO blood antigens First one made by newborns Largest immunoglobulin |
|
|
What is the primary immune response that a vaccination produces
|
Macrophage engulf
presents it to Th cell the Th cells activate B Cells B Cells produce Ig |
|
|
What is the secondary response
|
The response is more rapid
Memory cells take action Larger amounts of antibodies are produced |
