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15 Cards in this Set
- Front
- Back
Leukocyte |
All white blood cells of the immune system |
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Monocyte |
A cell that originates from a myeloid progenitor cell (DC or M) |
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Antigen presenting cell (APCs) |
A cell that functions to present antigens to other cells of the immune system (DCs or M) These cells phgocytose the pathogen directly and present the foreign antigen on their surface |
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Phagocytosis |
A type of endocytosis where large substances or small organisms (like bacteria) are teken up by the cell |
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Lymphocyte |
Cells that originate from a lymphoid progenitor (T cells, B cells, NKCs) |
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Humoral |
A part of the Adaptive Immune Response - involved B cells and Abs - Be cells recognize a pathogen and promt the plasma cells to produce Abs - Abs can clear the infection by Neutralization, Agglutination or by Compliment Fixation |
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Cell-Mediated |
A part of the Adaptive Immune Response - involves Cytotoxic T Lymphocytes (CTLs) which recognize MHC I complexes carrying foreign antigens on infected cells - CTLs kills these infected cells through perforin and granzyme mediated cell lysis |
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microbe |
a microscopic organism (bacteria, fungus, virus...) |
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pathogen |
an organism or virus that causes disease |
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parasite |
an organism that feeds on cell contents, tissues, or body fluids of another species (the host) while in or on the host organism |
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foreign antigen |
a substance that elicits an immune response by binding to B cell receptor, T cell receptors or antibodies |
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epitope |
a small region of an antigen to which a receptor protein or an antibody bind |
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Antibody (Abs) |
a protein secreted by plasma cells that has a "Y" shape and is made of 2 heavy chans + 2 light chains Abs bind to specific antigens Abs are also called Immunoglobulins |
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MHC I |
a complex of cell surface proteins that present antigens, found on all cells with a nucleus |
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MCH II |
A complex of cell surface proteins that present antigens Found ONLY on antigen presenting cells (DC or M) |