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8 Cards in this Set
- Front
- Back
Four categories of immune hypersensitivity reactions |
Immediate (Type I)hypersensitivity |
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Type 1 hypersensitivity classically mediated by.. |
IgE antubodies directed against specific antigens |
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Mast cells activation in Type 1 hypersensitivity |
C3a C5a Chemokines Drug (codeine morphine) Melliton Physical stimuli |
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Activation of mast cells and basophils in type 1 hypersensitivity |
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Mediators released in initial rapid response of type 1 hypersensitivity |
Biogenic amines, enzymes, proteoglycans |
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Mediators of second phase of type 1 hypersensitivity |
Lipid mediators Leukotrienes B4/ C4,D4,E4 Prostaglandin D2 PAF |
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Type III hypersensitivity is mediated by ? |
Antigen-antibody complex (immune complexes) |
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Three phases of systemic disease of type 3 hypersensitivity |
1. Formation of immune complexes 2. Deposition of immune complexes 3. Injury caused by immune complexes |