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14 Cards in this Set
- Front
- Back
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Macrophages are responsible for __________________ of ______________ and other foreign cells for ___________ of other immune cells
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phagocytosis, bacteria, activation
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What is defence against infections mediated by ?
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Early reactions of the innate immune system and later responses of the adaptive immune system
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True/false the innate immune response can eradicate the infection
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True
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What is the role of the lymphocyte expansion
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Helps to keep pace with rapidly dividing microbes
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Name three defence mechanisms that antibodies use against extracellular pathogens
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Opsonisation
Neutralization ADCC |
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Antibodies neutralising toxins is similar to
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Prevent by vaccination with toxoid
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Capsule does not induce strong antibody response
Why? |
Its not specific
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what are the characteristics T cell-independent antibody responses
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Short-lived and weak
Low affinity, poor memory0, few long-lived plasma cells More IgM than IgG |
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True/False T helper cell-dependent antibody responses to protein antigens are more effective
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True
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what are the characteristics of helper T cell-dependent antibody responses
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High affinity, good memory, long half life, long lived plasma cells; IgG, more IgA than IgM
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True/false helper t cell-dependent antibody responses are the reason for conjugate vaccines
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True
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What are the extracellular sites of infection
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Intersitial spaces, blood, lymph and epithelial
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Name the components of epithelial extracellular protective immunity
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Antimicrobial peptides, Antibodies especially igA
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What are the intracellular sites of infection
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Cytoplasmic and vesicular
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