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6 Cards in this Set
- Front
- Back
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Complement factors deficient in Classical pathway AND S/S?
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C1q, C1r, C1s, C4, C2 deficiency.
Marked increase in immune complex Dz, increased infection with pyogenic bacteria |
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Complement deficiency of the Alternative pathway AND what increased suseptibility to?
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Factor B or properdin - inability to make C3bBb or stabilize it.
Increased suspetibilty to Neisseria infections |
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Complement factor deficiency affecting both pathways AND S/S?
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C3
Recurrent bacterial infections, immune complex Dz |
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Complement factor deficiency affecting both pathways AND Increaed suspetibility?
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C5-C8
Menigicoccal and gonococcal infections |
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Complement factor deficiency affecting regulatory proteins?
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C1-INH leading to overuse of C1, C4, C2 causing hereditary angioedema
Dx by decreased C4 levels b/c of excess use of the early components |
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Complement factor deficiency affecting regulatory proteins causing paroxysmal nocturnal hemoglobinuria?
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Decay-activating factor or homologous restriction factor
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