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14 Cards in this Set
- Front
- Back
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What are the 2 B-Cell deficiencies?
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Bruton's agammaglobulinemia
Selective immunoglobulin deficiency |
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What are the 2 T-Cell deficiencies?
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Thymic aplasia (DiGeorge Syndrome)
Chronic mucocutaneous candidiasis |
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What are 3 B and T cell deficiencies?
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Severe Combined Immunodeficiency
Wiskott-Aldrich Syndrome Ataxia-telengiectasia |
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What are some phagocytic deficiencies?
(6) |
Chronic granulomatous
Chediak-Higashi Job's Syndrome Leukocyte adhesion deficiency syndrome Hyper-IgM syndrome IL-12 receptor deficiency |
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X linked recessive defect in tyrosine kinase gene; low levels of all classes of immunoglobulins ?
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Bruton's
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deficiency in isotype switching; IgA deficincy is most obvious --"> sinus and lung infections?
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selective immunglobulin deficiency
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Tetany; failure of 3rd and 4th pharyngeal pouches to develop...
recurrent viral and fungal infections |
DiGeorge's
thymus and parathyroids fail to develop |
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Triad of symptoms: pyogenic infections, eczema and thrombocytopenia
X-Linked |
Wiskott-Aldrich Syndrome
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Defect in early stem cell differentiation
mAY BE DUE TO ADENOSINE DEAMINASE DEFICIENCY, DEFECTIVE iL-2 RECEPTORS OR failure to synthesize MHC II antigens |
severe combined immunodeficiency
recurrent viral, bacterial, fungal infections no B or T cells |
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Defect in DNA reepair enzymes
IgA deficiency |
Ataxia-telengiectasia
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Lack of NADPH oxidase activity?
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Chronic granulomatous disease
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How would you test for chronic granulomatous disease?
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negative nitroblue tetrazolium dye reduction test
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Defect in microtubular function and lysosomal emptying of the phagocytic cells?
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Chediak -Higashi
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Failure of gamma-interferon production by helper T CELLS?
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Job's syndrome
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