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78 Cards in this Set
- Front
- Back
ET=essential tremor
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ET
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ET - cause
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unknown, but may be inherited
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ET - affected body parts
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head and hands
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ET - distinguished from Parkinsons by
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no hypokinetic/bradykinetic features
no rigidity |
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ET - onset
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any age
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ET - exacerbated by
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stresss
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ET - tx
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beta blockers
modest amount of ETOH |
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HD=huntington's disease
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HD
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HD - def
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highly genetic disorder characterized by choreiform movements, mental status, and personality changes
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HD - onset
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insidious between 30-50 yo
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HD - reflexes
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brisk
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HD - tongue
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inability to maintain tongue protrusion
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HD - CT
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cerebral atrophy
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HD - lab/csf
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normal
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HD - tx
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no cure
genetic counseling |
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HD - prognosis
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death 15 years after onset
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PD=parkinsons disease
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PD
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PD - def
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progressive degenerative disease from loss of dopaminergic neurons in the substantia nigra
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PD - inc
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common disorder, males>females
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PD - onset
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mean age 55
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PD - etiology
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genetic
drug induced |
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PD - clin man
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resting pill rolling tremor
cogwheel rigidity bradykinesia postural instability shuffling gate depression dementia |
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PD - tremor improves
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with movement
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PD - dx
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clinical
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PD - CT in order to
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rule out other pathology
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PD - tx
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levodopa plus carbidopa
dopamine agonists anticholinergics amantadine selegiline |
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PD - selegiline effect
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delays need for levodopa
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PD - amantadine effect
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helps all features, mech unknown
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PD - anticholinergics
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helpful with tremor and rigidity
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PD - levodopa plus carbidopa concern
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over time its lose their response to medication
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stroke - ischemic def
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insufficient blood flow to part or all of the brain
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stroke - ischemic neuro deficits
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last longer than 24 hours
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stroke - ischemic if neuro deficits < 24 hours consider
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TIA
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stroke - ischemic inc
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accounts for 60-65% of all strokes
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stroke - ischemic two
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thrombosis
embolism |
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stroke - ischemic thrombosis
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originates in site of occlusion
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stroke - ischemic embolism
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travelling thrombus
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stroke - ischemic embolism 3 types
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mural
valvular a-fib |
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stroke - hem def
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extravasation of blood into the brain
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stroke - hem inc
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15% of all strokes
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stroke - lacunar def
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caused by occlusion of small arteries
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stroke - lacunar inc
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20% of all strokes
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stroke - lacunar etiology
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longstanding hypertension
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stroke - risk factors
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age
afib htn smoking DM |
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stroke - clin man depends on
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location
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stroke - anterior cerebral sx
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neglect of contralateral leg
urinary incontinence |
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stroke - basilar artery sx
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bilateral sensory
cranial nerve abnormalities paralysis of all extremities impaired vision |
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stroke - internal carotid sx
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ipsilateral blindness
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stroke - middle cerebral sx
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contralateral wekaness
sensory loss face/arm expressive aphasia spatial disorientation |
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stroke - posterior cerebral sx
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difficulty reading and performing calks
memory impairment |
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stroke - vertebral artery
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vertigo
NV nystagmus |
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stroke - dx
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neuro exam
EKG carotid doppler |
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stroke - MRI
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more sensitive for detecting early ischemia
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stroke - imaging
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CT, no contrast
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stroke - preventative tx
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modify risk factors
ASA control HTN |
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stroke - thrombolytics timeframe
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within 3 hours
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stroke - thrombolytics must have
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CT to rule out hemorrhage
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stroke - thrombolytics BP target
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lower than 180/110
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stroke - thrombolytics contraindications
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trauma/surgery within 2 weeks
GI bleed |
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stroke - hemorrhagic tx
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mannitol
head elevation hyperventilation |
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stroke - prophylaxis
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heparin
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CP=cerebral palsy
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CP
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CP - def
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non progressive disorder ofo movement and posture due to lesion in immature brain
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CP - inc
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most common movement disorder of children
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CP - risk factors
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premature
birth asphyxia intrauterine growth retardation infection trauma |
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CP - infants initially
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hypotonic
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CP - two types
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pyramidal
extrapyramidal |
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CP - pyramidal def
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tone remains constant despite activity with primitive reflexes present and significant hyperreflexia
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CP - pyramidal 4 types
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diplegia
quadriplegia hemiplegia bilateral hemiplegia |
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CP - extrapyramidal def
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tone is variable depending on level of arousal
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CP - extrapyramidal 3 types
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ataxic - coordination problems
choreoathetoid and dystonic - uncontrollable |
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CP - common neuro deficits
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seizures
mental retardation hearing and vision |
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CP - tx
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no cure
maximize fx |
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PD - elderly most affected sklls
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motor skills
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PD - elderly clin man trifecta
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bradykinesia
tremor rigidity |
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PD - elderly meds consideration
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acute confusion and psychotic sx can be provoked by the medications
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PD - if PD and dementia sx are both evident
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it's considered PD if the motor sx appear first
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PD - v. DLB (dementia with lewy bodies
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DLB is
insidious, but faster cognitive and behavioral disturbances predominate |