Iiii

Front 1

Susceptible to hydrolysis by lactamase.

Back 1

Penicillin G

Front 2

Treat infection caused by MSSA

Back 2

Penicillinase Resistant Pen

Front 3

Used in empiric therapy in community acquired infections involving respiratory tract

Back 3

Aminopenicillin

Front 4

A prototype drug, used in the 1st line treatment of UTI

Back 4

Ampicillin

Front 5

Good bioavailability and not altered by food but can cause diarrhea

Back 5

Amoxicillin

Front 6

4x more potent than Ticarcillin

Back 6

Piperacillin

Front 7

A sodium containing antibac

Back 7

Carbenicillin

Front 8

8x more potent than Carboxypenicillin

Back 8

Ureido penicillin

Front 9

It resembles the act of Ticarcillin

Back 9

Mezlocillin

Front 10

4x more potent than Carbenicillin

Back 10

Ticarcillin

Front 11

DOC for Prophylaxis and treatment of Anthrax

Back 11

Ciprofloxacin

Front 12

Used in the tx of Prostatitis due to E. Coli and STD

Back 12

Levofloxacin

Front 13

Used for the treatment of bacterial gastroenteritis and cholecystitis

Back 13

Sparfloxacin

Front 14

2nd gen quinolones used in the treatment of acute chronic bronchitis

Back 14

Lomefloxacin

Front 15

DOC for amoebiasis, giardiasis, and trichomonas infection

Back 15

Metronidazole

Front 16

Structurally related to beta lactam antibiotics

Back 16

Carbapenem

Front 17

1st monobactams

Back 17

Sulfacezin

Front 18

Similar to Emipenem but has a greater activity

Back 18

Dorpinem

Front 19

Less active than the other carbapenems

Back 19

Ertapenem

Front 20

Associated with Red Man Syndrome

Back 20

Vancomycin

Front 21

A semi synthetic lipoglycopeptide from Vancomycin

Back 21

Telavancin

Front 22

Similar to Vancomycin

Back 22

Teicoplanin

Front 23

A semi synthetic lipoglycopeptide from Teicoplanin

Back 23

Dalbavancin

Front 24

Obtained from the Tracy strain of B. Subtilis in 1943.

Back 24

Bacitracin

Front 25

Used to treat tuberculosis caused by strains of Mycobacterium tuberculosis resistance to 1st line agents.

Back 25

Cycloserine

Front 26

These are formed by catalytic reduction of Chlortetracycline

Back 26

Tetracyclines

Front 27

Most potent tetracycline

Back 27

Minocycline

Front 28

1st glycylcycline

Back 28

Tigecycline

Front 29

Inhibits the action of ADH and most stable than Tetracycline

Back 29

Demeclocycline

Front 30

This is an alternative drug for patients allergic to Penicillin and Cephalosporin

Back 30

Erythromycin

Front 31

Derived from Erythromycin with the addition of methyl group

Back 31

Clarithromycin

Front 32

A 15-atom lactone derived from Erythromycin with the addition of methylated nitrogen

Back 32

Azithromycin

Front 33

More lipid soluble prodrug that is alternative to Erythromycin

Back 33

Dirithromycin

Front 34

Resembles Erythromycin but with ketone macrolides

Back 34

Ketolides

Front 35

Only ketolide approved in the market for clinical used

Back 35

Telithromycin

Front 36

It is widely known for the treatment of acne

Back 36

Clindamycin

Front 37

. It is used in the treatment of Typhus and Rocky Mountain Spotted Fever

Back 37

Chloramphenicol

Front 38

This drug may cause an absent or decrease in lubrication in the synovial fluid

Back 38

Quinupristin

Front 39

Most active aminoglycosides and used as 2nd line agent treatment for TB

Back 39

Streptomycin

Front 40

An aminoglycoside that is used in the mgt of severe infection like sepsis and used as 2nd liner treatment for UTI

Back 40

Gentamicin

Front 41

This drug is 1st synthesised by Gerhard Domagke

Back 41

Prontosil

Front 42

A. 6-aminopenicillanic acid is the active form of Penicillin

B. Only D-alanine is targeted by Penicillin

Back 42

Only the 1st statement is true

Front 43

A. Pen G is administered orally B. Pen V is administered parenterally

Back 43

Both false

Front 44

A. PBP1 causes cell lysis B. PBP1 are AMOXICILLIN AND CEPHALOSPORIN

Back 44

Both true

Front 45

A. PBP3 has no cell division B. PBP4 has no lethal effect

Back 45

Only the 2nd is true

Front 46

A. Oxacillin has no chlorine in the structure B. Dicloxacillin has 2 chlorine

Back 46

Both true

Front 47

A. Ampicillin + Sulbactam = Augmentin B. Amoxicillin + Cluvanic = Unasyn

Back 47

Both false

Front 48

A. All protein synthesis are STATIC except Aminoglycosides

B. All anti-TB agents are CIDAL except Ethambutol

Back 48

Both true

Front 49

A. Extended spectrum is the most effective antimicrobial agents

B. Narrow spectrum are effective against gram positive and gram negative bacteria

Back 49

Both false

Front 50

A. 7-aminocephalosporanic acid is the active form of Cephalosporins

B. They prevent cell wall thru the PBP

Back 50

Both true

Front 51

A. 2nd gen Cephalosporins decreased absorption with food

B. 3rd gen Cephalosporins are not induced enterohepatic circulation

Back 51

Both false

Front 52

A..Tobramycin has almost the same antibacterial spectrum as Gentamicin

B. Amikacin is a semisynthetic derivative of Kanamycin

Back 52

Both true

Front 53

A. Spectinomycin is used as an alternative treatment for drug resistant gonorrhoea

B. Netilmicin may be active against some Gentamicin-resistant and tobramycin resistant bacteria

Back 53

Both true

Front 54

A. Sulfisoxazole and Sulfamethoxazole are used as 1st mgt of UTIB.

B. Sulfadiazine + Pyrimethamine are used as 1st line for acute toxoplasmosis.

Back 54

Both true

Front 55

A. Trimethoprim can be given alone in acute UTI

B. The dose given is 100 mg once a da

Back 55

Only the 1st statement is true

Front 56

A.Oral TMP-SMZ is the agent choice for moderately to severe pneumocystispneumonia

B. IV TMP-SMZ is effective treatment for a wide variety of infection

Back 56

Both false

Front 57

A. Oral Pyrimethamine with Sulfonamide is used to treat Leishmaniasis

B. It has a side effect of bone marrow depression.

Back 57

Both true

Front 58

A. Fluoroquinolones are synthetic fluorinated analogs of nalidixic acid

B. Quinolones block bacterial DNA synthesis by inhibiting Topoisomerase II andTopoisomerase IV.

Back 58

Both true

Front 59

A. Norfloxacin is most active

B. Ciprofloxacin is less active

Back 59

Both False

Front 60

A. Bactericidal means that microorganisms have the ability to inhibit the growth ofbacteria

B. Bacteriostatic means that the microorganisms have the ability to kill the bacteria.

Back 60

Both false

Front 61

A. Drug resistance is the susceptibility of pathogenic microorganisms to drugs lower or even lose after contact with drugs many times.

B. Cross resistance is when the bacteria show resistance to one drug, they are also resistant to some other drugs

Back 61

Both true

Front 62

1st line treatment for UTI

Back 62

Ampicillin