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16 Cards in this Set
- Front
- Back
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How thick are cellular membranes?
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7.5 to 10 nanometers thick
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celleular membranes are ___ of lipids and proteins
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fluid mosaics
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__-are the most abundant lipids in the plasma membrane
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phosholipids...they are amphipathic and contain both hydrophobic an dhydrophilic regions
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phosphoglyceride
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phospholipid
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phosphatidylcholine
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phospholipid
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sphingomyelin
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phospholipid
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glycolipids
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have lipid and then a sugar
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asymmetric bilayr membrane
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cytoplasmic side more acidic
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Immune cells can see the exposed
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phoshatidylserine on the extracellular surface so it will set out to destroy it.
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temperature affects fluidity of lipid bilayers
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increase temperature will increase fluidity...can be affected by cholestrol
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type of hydrocarbon tail and fluidity
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saturated tails decrease fluidity and unsaturated increases fluidity
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steroid cholesterol affect fluidity
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normalizes the fluidity to around Tm
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lipid rafts
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sphingolipid and cholesterol-dependent microdomains in the plasma membrane
important role in immune cell |
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lipid rafts tend to be thicker than adjacent membrane areas. proteins with fatty acyl or glycosylphosphatidylinositol____tend to associate preferentially with raft domains.
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lipid anchor
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MIRR signaling
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multichain immune recognition receptors signaling when rafts get together
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Only proteins with specific modifications can enter rafts such as...
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palmytoylation
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