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45 Cards in this Set
- Front
- Back
define tremor
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rhythmic, sinusoidal, oscillatory movement due to regular contraction of reciprocally innervated antagonistic muscles
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what disease has resting tremor?
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parkinson disease
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what disease has postural (action) tremor?
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essential tremor and physiologic tremor
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what disease has kinetic tremor (with movement)?
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essential tremor
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what disease has intention tremor (terminal accentuation)?
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cerebellar disease
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your grandma's hands shake and her voice tremors, but it gets better after a G&T. What does she have?
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essential tremor
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define chorea
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jerky, irregular, non-repetitive, brief, semi-purposive movements that flit from one body part to another in a random sequence
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when I say jack in the box tongue, you say
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chorea
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when I say 'hung-up' reflex, you say
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chorea
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when I say milkmaid's grip, you say
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chorea
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do patients with chorea have hypertonia or hypotonia?
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hypotonia
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what are the 4 choreiform disorders?
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1. hungington disease; 2. sydenham's chorea (rheumatic fever), 3. L-dopa induced dyskinesias (only in parkinsons), 4. tardive dyskinesia (not a true chorea, seen in psychophrenia
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what is tardive dyskinesia?
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a hyperkinetic movement disorder, appears after months of therpay with D blockers (can develop even after drugs have been discontinued)
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what types of movements are seen in tardive dyskinesia?
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patterned - orobuccolingual choreiform movments "wormiform" movements in tongue
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define Tics
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repetitive, irregular stereotypic movments or vocalizations that can be suppressed only for a short time
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define myoclonus
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rapid breif shock like muscle jerks that involve one or more sites in a repetitive fashion
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Define asterixis
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"flapping tremor", it is a form of negative myoclonus - secondary to lapse in msucle tone
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what are the causes of asterixis?
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hepatic failure, uremia, hypercarbia, hyponatremia, drug induced (phenytoin or carbamezepine toxicity)
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define hemiballismus
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uncontrollable violent jerky movements of large amplitude involving proxmial muscles on one side
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where is the lesion for hemiballisum?
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contralateral subthalamic nucleus of Luys - usually vascular etiology
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what is unique about hemiballisum?
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It IS ACUTE - the only one that is acute!
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define dystonia
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a syndrome of sustained muscle contractions frequently causing repetitive movements or abnormal postures
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what population is affected by focal dystonia?
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older
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what population is affected by generalized dystonia?
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younger
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What is Wilson's disease?
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AR disorder of copper metabolism that affects younger persons
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what are the signs of wilson disease?
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resting and or intention tremor, dystonia, chorea, dementia, psychiatric symptoms, dysarthria (cirrhosis and hemolytic anemia)
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What is the hallmark of wilson disease?
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Kayser-Fleischer rings in the eyes
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what is parkinson disease?
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a progressive neuro-degenerative disorder caused by degeneration of dopaminergic cells int eh substantia nigra pars compacta
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what is parkinsonism?
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bradykinesia, resting tremor, rigidity and postural instability
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what are the symptoms of brown-Sequard syndrome?
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ipsilateral weakness and UMN signs, ipsilateral proprioceptive deficits, contralateral superficial sensation deficits
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what are the symptoms of anterior spinal artery syndrome?
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bilateral weakness and UMN signs, bilateral superficial sensory deficitys, preserved proprioception
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where is a syringomyelic syndrome most likely to occur?
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cervical spinal cord
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what are the symptoms of syringomylic syndrome?
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upper limbs weaker than lower limbs, upper limbs - LMN signs; lower limbs - UMN signs
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what are the symptoms of central cord syndrome?
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upper limbs weaker than lower limbs, proximal weaker than distal, "man in the barrel syndrom"
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what are the symptoms of complete cord transection?
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clear sensory level, plegia below injury, anesthesia below injury, initially flaccid then spastic bladder, autonomic dysreflexia if T6 or higher
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what are the symptoms of conus syndrome?
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early sphincter signs, flaccid bladder and bowels (retention), impotence, saddle anesthesia and decreased anal tone
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what are the symptoms of cervico-medullary junction syndrome?
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clockwise or counter-clockwise progression or weakness, commonly starts with UL monoparesis; downbeating nystagmus, lower cranial nerve symptoms
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where is central cord syndrome most likley to occur?
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cervical spinal cord
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what are the symptoms of spinal shock?
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decreased muscle tone, flaccid bladder, severe orthostasis and absent superfical reflexes
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what should you think if there are absent superficial reflexes after a spinal cord injury?
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spinal shock
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what presents with paraparesis/tetraparesis, bowel and bladder dysfunction, brisk reflexes, bilateral babinski and sensory loss?
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acute transverse myelitis
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what is acute transverse myelitis associated with in children?
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post infection
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what is acute transverse myelitis associated with in young adults?
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MS, not uncommon - post infection
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what is acute transverse myelitis associated with in older adults?
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mass lesion, Zoster infection, ischemia
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What is the most common disabling neurological disease of the middle aged?
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MS
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