Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
13 Cards in this Set
- Front
- Back
|
How many strands of RNA does HIV have in its capsid?
|
2 (positive, ss)
|
|
|
Which of these proteins is incorrectly matched to its other name?
a.) p24 - capsid b.) p17 - integrase c.) gp120 - surface d.) gp41 - transmembrane |
b.) p17 - actually matrix
|
|
|
tat
|
transcriptional activator; induces apoptosis in uninfected cells
|
|
|
nef
|
downregulates CD4 protein expression, priming T cells for virus replication. Nef-deficient HIV leads to non-progressors
|
|
|
vpr
|
virion assoc protein - causes T cells to arrest in G2 stage of cell cycle, causing apoptosis of infected cells
|
|
|
vif
|
prevents deamination of viral DNA by cellular protein (preventing deadly mutation to virus)
|
|
|
vpu
|
influences viral release
|
|
|
rev
|
post-transcriptional transactivator
|
|
|
Describe how HIV can kill via
a.) direct killing b.) syncytium formation c.) immune attack d.) apoptosis |
a.) HIV interferes with normal cellular gene expression, loss of cell membrane, & accum of cytotoxic viral DNA
b.) uninfected CD4 cells bind to HIV infected cells. These die. c.) shed gp120 can attach to uninfected CD4 cells and mark them for killing. Also CTL killing of infected cells. d.) Tat mediates apoptosis of uninfected cells. |
|
|
Which of these is the confirmatory test for HIV?
a.) Rapid HIV testing b.) ELISA c.) Western blot analysis d.) HIV RNA (viral load) testing e.) CD4 cell count f.) genotypic & phenotypic resistance testing |
c.) Western blot analysis
|
|
|
At what CD4 cell count should you begin treating an asymptomatic HIV infection?
a.) any value b.) below 200 c.) below 350 d.) below 450 |
c.) below 350
|
|
|
At what CD4 cell count should you begin treating an asymptomatic HIV infection in a pregnant woman?
a.) any value b.) below 200 c.) below 350 d.) below 450 |
a.) any value
|
|
|
Which of these is not like the others?
a.) pox virus b.) herpes virus c.) echovirus d.) papilloma virus e.) parvo virus |
c.) echovirus - this is the only RNA virus
|
