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26 Cards in this Set
- Front
- Back
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this arthropod is the vector for lyme disease
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ixodes scapularis "deer tick"
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causative agent of lyme disease?
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borrelia burgdoferi
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treponema and borrelia are both under what group?
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spirochete
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natural reservoir of B. burdorferi?
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white footed mouse (peromyscus leucopus)
accidental host : dogs, deer, humans |
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early manifestations of lyme disease?
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**erythema migrans
carditis (can lead to heart block) aseptic meningitis Bell's palsy |
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late manifestations of lyme disease?
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arthritis (90% knee)
CNS disease |
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Dx of lyme disease?
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serology - ELISA
confirm w/ western culture PCR early on, serology may be negative -> Dx via clinical presentation and Tx accordingly |
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Tx of lyme disease?
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doxy or amoxicillin
if complications -> IV ceftriaxone |
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agent of rocky mountain spotted fever?
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rickettsia rickettsi
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characteristics of rickettsia?
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obligate intracellular parasite
gram negative coccobacilli |
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what's special about incidence of rocky mountain spotted fever?
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it's seasonal (spring- summer)
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Sx and sign of RMSF
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incubation period 2-14 days
early Sx: fever, headache, myalgia rash begins few days after onset - petechial, peripheral distribution |
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what type of cells do rickettsia infect?
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endothelial cell
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lab Dx of RMSF?
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not very good
seroconversion or rise in titer visualization in biopsy |
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Tx of RMSF
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doxy
chloramphenicol |
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two types of ehrlichiosis
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human granulocytotropic ehrlichiosis
human monocytotropic ehrlichiosis |
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characteristics of ehrlichia
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gram negative, coccoid
obligate intracellular parasite live and replpicate within phagosomes can't be grown on cell free media |
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life cycle of ehrlichia
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entery -> elementary body -> initial body -> morula -> release
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two agents of ehrlichia?
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ehrlicia chaffeensis
anaplasma phagocytophilaa |
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reservoir for ehrlicia chaffeensis and
anaplasma phagocytophilaa ? |
e, chaff - white tailed deer
a phagocytophila - white footed mouse |
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season/epidemiology of ehrliciosis?
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spring-summer
middle aged/ elderly adults |
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vector of ehrliciosis?
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ixodes ticks
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manifestations of ehrlichiosis?
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fever, headache, myalgia
1/3 have maculo papular rash **lab - decrease in all cell lines esp WBC and platelets |
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severe ehrlichiosis?
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meningitis
pneumonitis severe hepatitis hemphagocytic syndrome disseminated intravascular coagulation |
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Dx of ehrlichiosis??
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microscopy
culture serology PCR *remember to start Tx b4 Dx |
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Tx of ehrlichiosis?
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doxy
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