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41 Cards in this Set

  • Front
  • Back
What is the Centor Criteria for strep pharyngitis?
1. Absence of cough
2. History of fever
3. Tender ant. cerv. LAD
4. Tonsillar exudates
What is Ludwig's angina?
Severe cellulitis of the tissue of the floor of the mouth with involvement of bilateral submandibular and sublingual spaces
What are the main bacteria indicated in Ludwig's angina?
Strep and anaerobes
What should be suspected if sx of AOM have persisted for > 2 weeks?
Mastoiditis
Neck masses: probable inflammatory cause vs. cyst or tumor
Inflammatory: painful, soft or fluctuant nodule
Cyst/tumor: painless, firm mass
Patient presents with a smooth, fluctuant mass underlying the SCM that appeared rapidly after a URI. This is most likely what?
Branchial Cleft Cyst
What is the most common congenital neck mass?
Thyroglossal Duct Cysts
Fever + pulmonary infiltrate + erythema nodosum + recent trip to Central America =
Histo or Coccidiomycosis
Mass lung lesion in Midwestern farmer =
Could be Blasto
What is the most common non-pigmented acutely branching septate filamentous fungus that causes infections in immunocompromised hosts?
Aspergillus
Leukemia patient presents with recent neutropenia, fever, RUQ pain, nausea and elevated alkaline phosphatase. This is likely...
Chronic disseminated candidiasis
How does one treat invasive aspergillosis? Refractory invasive aspergillosis?
Invasive aspergillosis: Amphotericin B or voriconazole
Refractory: Echinocandins
What are the mechanisms of action of the following anti-fungal classes?
1. Azoles
2. Echinocandins
3. Polyenes (Ampho B)
1. Impairs ergosterol synthesis
2. Impairs B 1,3 glucan synthesis
3. Binds to ergosterol
Name an echinocandin
Caspofungin
Where is blastomycosis endemic?
SE and south-central states on the Mississippi and Ohio River Basins, midwestern states, New York along St. Lawrence River
T/F: Blastomycosis is only a disease of immunocompromised hosts.
False
Describe a skin lesion from blastomycosis.
Begins as a papule, then progresses to elevated lesion with verrucous borders and ulcerated center.
Treatment for pulmonary blasto
Itraconazole (amphotericin B if disseminated, life-threatening)
How long are patients treated for candidemia?
14 days after last positive blood culture
How does acute cholangitis develop?
From obstruction, stasis and bacterial infection of the biliary tree
What five bacteria are commonly associated with cholangitis?
E. coli, Klebsiella, Enterobacter, Enterococci, and anaerobes
What is the HELLP syndrome of preeclampsia?
Hemolysis, elevated LFTs, low platelets
What is the key to treating intra-abdominal infections?
Drain all pus, remove all ischemic tissue
What organisms are most commonly indicated in intra-abdominal infections?
ANAEROBES, aerobic gram neg. rods, enterococcus, candida
26 yo female with h/o PID presents with fever, chills, left sided pelvic pain and leukocytosis. Be suspicious of...
Tuboovarian abscess
Patients with diverticulitis often present with pain in the _____.
LLQ
What antibiotics typically treat uncomplicated diverticulitis? What is the usual duration of treatment?
PO: Cipro + Flagyl or Augmentin
IV: Zosyn or Cefotetan + Flagyl
What type of patients are at high risk for spontaneous bacterial peritonitis?
Patients with underlying cirrhosis and ascites
How is the diagnosis of SBP made?
PMN count of >250 cells/mm3 with positive culture of ascitic fluid
Difference between SBP and alcoholic hepatitis
Alcoholic hepatitis does not cause an elevation in ascitic PMN count
What is the most common obligate anaerobe cultured after a colonic perforation?
B. fragilis (most common isolate in general is E. coli, then B. fragilis)
Important coverage in intra-abdominal abscess
Gram neg and anaerobic
Treatment for H. pylori
1 PPI + bismuth subsalicyte + tetracycline + metronidazole
What should be considered in any patient who develops diarrhea up to 6 weeks after abx exposure?
C. diff infection
Treatment for C. diff
Flagyl, oral vanco, cholestyramine as adjunct, rifampin added for prolonged cases
Which organisms responsible for gastroenteritis shift the balance of water and electrolyte fluxes but do not invade the intestinal mucosa?
Cholera, enterotoxigenic e. coli, clostridium perfringens, S. aureus, B. cereus
Which GE-causing organisms invade the colon and terminal ileum, destroying segments of intestinal mucosa and causing inflammatory changes?
Shigella, Campylobacter, Yersinia enterocolitica, Vibrio, Invasive E. coli, Salmonella
What GE-causing organism can transverse intact intestinal mucosa?
S. typhi
What organism causes Bacillary Dysentery?
Shigella
Preschooler presents with fever of 104, N/V, abdominal pain, and frequent loose bowel movements containing blood, mucus, and pus. What test could indicate the likely diagnosis?
Stool culture indicative of Shigellosis
Preferred treatment for Shigellosis
Adults: FQs
Children: Zithromax
*NO anti-diarrheals!*