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49 Cards in this Set

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CAP: non-severe
S. pneumonia, H. influenzae, Mycoplasma or Chlamydia
Levoquin or Zithromax/Rocephin
CAP: severe
Gram negative rods PLUS S. pneumoniae, H. influenzae, mycoplasma or chlamydia
Levoquin OR Zithromax and Zosyn OR Cefepime
Suspected aspiration pneumonia
Anaerobes
Clindamycin/Zosyn
Hospital Acquired Pneumonia
Gram negatives, E. coli, Enterobacter, Pseudomonas, Klebsiella
Pseudomonas, Gram negatives: Zosyn OR Cefepime OR Cipro +/- tobramycin
MRSA: Zyvox
HAP: Staph aureus
Nafcillin
Blastomycosis
Itraconazole (Amphotericin B for life-threatening infection)
Histoplasmosis
Itraconazole (Amphotericin B for meningeal infections)
Cryptococcus
Amphotericin B +/- 5-flucytosine
Chronic suppression of cryptococcus in HIV patients
Fluconazole
Candida albicans (superficial)
PO: Fluconazole
Topical: miconazole, nystatin, clotrimazole, ketoconazole
Candida esophagitis
Fluconazole
Candida albicans - deep seated infection
Amphotericin B
Cholecystitis
Coliforms and enterococci
Cefoxitin OR Zosyn
Cholangitis
Enterics, enterococci, anaerobes
Cefoxitin OR Zosyn
Diverticulitis
Enterics, anaerobes
Cefoxitin OR clindamycin OR zosyn or flagyl + tobramycin
Intra-abdominal infection
Enterics, anaerobes, enterococci
Zosyn OR Clindamycin OR Flagyl + Tobramycin/Ancef
Cystitis
E. coli, Staph saprophyticus
Bactrim, Cefadroxil, Nitrofurantoin, Fosfomycin, Quinolone (Cipro)
Pyelonephritis (community)
E. coli, Proteus
Bactrim OR Tobramycin OR Cipro/Levoquin
Pyelonephritis - nosocomial (underlying GU disease)
Gram negatives including E. coli, Pseudomonas, Enterococcus
Ampicillin + tobramycin OR Ancef + ampicillin
Prostatitis: acute
Under 35 years old: Neisseria gonorrhoeae or Chlamydia
Over 35 years old: Enterobacteriaceae
Under 35 years old: Ceftriaxone OR Cipro + Doxycycline
Over 35 years old: Bactrim OR Cipro
Prostatitis: chronic
Enterobacteriaceae, Enterococcus
Bactrim OR Cipro
Cellulitis (non-diabetic)
Streptococcus or Staphylococcus
Nafcillin (oral dicloxacillin), Clindamycin or Cefazolin in non-anaphylactic PCN allergy
Suspect MRSA - Vancomycin
Decubitus ulcer/diabetic ulcer
Staphylococcus, Streptococcus, Gram negatives, anaerobes
PO: Augmentin
IV: Zosyn OR Clindamycin OR Flagyl + Tobramycin
Necrotizing fasciitis
Streptococcus, Staphylococcus, Gram negative aerobes, anaerobes
PCN + Clindamycin + Tobramycin (or Cipro) OR Zosyn OR Merapenam
Human/animal bites
Pasteurella multocida, Streptococcus, Staphylococcus
IV: Cefuroxime
PO: Augmentin
Osteomyelitis: acute (hematogenous)
Staph aureus (common)
Gram negatives (less common)
S. aureus: nafcillin + rifampin OR nafcillin + tobramycin
Gram negatives: ciprofloxacin or ceftriaxone
Diabetic foot or contiguous ulcer
Gram negatives
Gram positives
Anaerobes
Zosyn +/- tobramycin
Septic arthritis: sexually active young adult
Neisseria gonorrhoeae, gonococcus
Ceftriaxone OR Ciprofloxacin + doxycycline
Septic arthritis: adult
Staph aureus
Group A streptococcus
Gram negative aerobes
Nafcillin +/- tobramycin +/- rifampin OR ceftriaxone +/- rifampin
Septic arthritis: with prosthesis
Staph epidermidis
Staph aureus
Gram negatives
Vancomycin OR ceftriaxone (+ rifampin if S. aureus)
Meningitis: ages 18-50 (community)
S. pneumoniae
N. meningitis
H. influenzae
Ceftriaxone + vancomycin + ampicillin (+ dexamethasone)
Meningitis (immunosuppressed)
Community acquired pathogens
Listeria monocytogenes
Fungal
Mycobacterial
Ampicillin +ceftriaxone + vancomycin
Viral encephalitis/meningoencephalitis
Herpes simplex
Acyclovir
Acute sinusitis
S. pneumoniae
H. influenzae
M. catarrhalis
Amoxicillin OR cefuroxime OR Augmentin
Chronic sinusitis
S. pneumonia
H. influenzae
M. catarrhalis
+ S. aureus
Augmentin or Clindamycin
Hospital acquired sinusitis
Gram negative aerobes
S. aureus
Anaerobes
Levoquin OR Azithromycin + Zosyn OR cefepime
Exudative pharyngitis
Group A strep
Penicillin *watch for mono!*
Vesicular/ulcerative pharyngitis
Coxsackie or Herpes simplex virus
Acyclovir
Epiglottitis
Group A strep OR H. influenzae
Cefuroxime OR ceftriaxone
Periorbital/Orbital cellulitis
Strep species
Staph species
H. influenzae
Anaerobes
Cefuroxime OR ceftriaxone (consider fungal etiology if immunosuppressed)
Otitis media
S. pneumoniae
H. influenzae
M. catarrhalis
Amoxicillin OR Augmentin OR cefuroxime
Acute mastoiditis
S. pneumoniae
S. pyogenes
S. aureus
Cefuroxime
Chronic mastoiditis
Polymicrobial: pseudomonas, S. aureus, anaerobes
Tobramycin + Zosyn (requires surgery)
Urethritis/Cervicitis/Prostatitis
N. gonorrhoeae
Chlamydia
Ceftriaxone OR Ciprofloxacin + doxycycline OR Zithromax
PID
N. gonorrhoeae
Chlamydia
Bacteroides
Enteric gram negatives
Outpatient: Ceftriaxone + doxycycline
Inpatient: Cefotetan +doxycycline
Herpes simplex
HSV
Acyclovir, valcyclovir
Chancroid
Haemophilus ducreyi
Ceftriaxone OR erythromycin OR azithromycin
Syphillis
Treponema pallidum
Benzathine PCN
Neurosyphillis
T. pallidum
Penicillin G