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32 Cards in this Set
- Front
- Back
What are the layers of the skin?
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epidermis and dermis separated from underlying fascia by the hypodermis
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What are the inner and outer layers of the epidermis?
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Most inner: stratum basale, Most outer: stratum corneum (keratinized)
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What structures are part of the dermis?
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connective tissue, hair follicles, sebaceous and sweat glands, blood and lymph vessels, nerves
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What is the hypodermis comprised of?
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connective and adipose tissue
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What are the immune cells of the skin?
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Langerhans cells (antigen presenting cells), Mast cells, IgG
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What is the purpose of the normal skin flora?
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colonize surface of epidermis and hair follicles and inhibit colonization by other microorganisms
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What factors influence the quantity and type of resident flora? What type of bacteria predominate?
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skin pH, moisture, fatty acids, other factors; gram positive bacteria predominate
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What is the most common normal flora that is a gram negative rod? fungi?
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gram neg rod: Acinetobacter spp; Fungi: Malassezia pachydermatis, Candida albicans
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How are the transient flora of the skin acquired?
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acquired from environment or mucosal membrane flora (remain for days to weeks)
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What is Otitis Externa? What are the common agents in normal and abnormal ears?
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inflammation of external ear canal, staph pseudintermidius, Staph felis, beta-hemolytic Strep spp, Malassezia pachydermatis
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What agents are only found in abnormal ears?
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gram negative bacteria: Pseudomonas aeruginosa, Escherichia coli, Proteus mirabilis, Klebsiella pneumoniae
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What are the predisposing factors of Otitis externa?
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breed, ear conformation, neoplasms, allergies, seborrhea, environment (moisture, trauma, foreign bodies, cleaning agents), other agents (Otodectes cynotis, demodex, sarcoptes, notoedres)
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What are the clinical signs of otitis externa?
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pruritus, head shaking, rubbing of ears against things, head shyness (pain); ear canal is reddened, often swollen, and may have moderate to large amounts of discharge, may have an odor
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What are some more clinical signs of otitis externa?
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attempts to scratch ear with ipsilateral hind paw, lesions on pinna and caudal to pinna on head, aural hematomas, severe cases may have head tilt
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What is dry coffee ground-like debris typical of?
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ear mite infection
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What is waxy, greasy, yellow to tan discharge typical of?
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ceruminous otitis; keratinization disorders, endocrine conditions, chronic hypersensitivity
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What is moist brown discharge typical of?
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staph and yeast infections
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What is purulent creamy to yellow exudate typical of?
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gram neg infections
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How is otitis externa diagnosed?
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otoscopic exam; cytological exam for bacteria, yeasts, mites; DQ stain for bacteria and fungi (>5 yeasts and/or >25 bacteria per high dry field)
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What is a clinical sign of chronic otitis externa?
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epidermal hyperplasia with thickening of pinna and narrowing or calcification of the ear canal
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When is culture and sensitivity used?
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cases that do not respond to current therapy or that may need systemic abx; take sample within the horizontal ear canal
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Why is sensitivity testing usually not needed in cases of otitis externa?
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concentrations of drugs used topically are much greater than what is present in the sensitivity discs
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What is the treatment of otitis externa?
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determine and eliminate and/or control predisposing factors; treat proper ear cleaning; topicals; systemic abx (middle ear infection or topicals can't be applied to ear)
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What is the etiologic agent of Malassezia Dermatitis? morphology?
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Malassezia pachydermatis; lipophilic yeast found as commensal on skin and mucocutaneous areas of dogs and cats
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Where on the animals are the highest numbers of M pachydermatis found?
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chin and lips, external ear canal, perianal regions, and dorsal interdigital areas
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What are the clinical signs of infection with M pachydermatis?
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pruritis, alopecia w/ erythema (reddened), seborrhea, hyperpigmentation, lichenification (thick and scaley), sour smell
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Where on the animal are common affected areas?
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interdigital, ventral neck, perianal, face, and axillary regions
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What are the predisposing factors that allow proliferation of the yeast?
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allergies, seborrhea, excessive bathing
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What causes clinical signs to develop due to M pachydermatis?
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allergic reaction to metabolic by-products of the yeast
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How is infection with M pachydermatis diagnosed?
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clincial signs, demonstration of yeast cells on skin scraping: small broad-based yeast cells
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What is the therapy for M pachydermatis?
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determine and treat predisposing factors; treat topically (shampoos or dips): miconazole, ketoconazole, clotrimazole, nystatin; consider oral azoles; *griseofulvin is ineffective
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What is the zoonotic potential?
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very low
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