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32 Cards in this Set

  • Front
  • Back
What are the layers of the skin?
epidermis and dermis separated from underlying fascia by the hypodermis
What are the inner and outer layers of the epidermis?
Most inner: stratum basale, Most outer: stratum corneum (keratinized)
What structures are part of the dermis?
connective tissue, hair follicles, sebaceous and sweat glands, blood and lymph vessels, nerves
What is the hypodermis comprised of?
connective and adipose tissue
What are the immune cells of the skin?
Langerhans cells (antigen presenting cells), Mast cells, IgG
What is the purpose of the normal skin flora?
colonize surface of epidermis and hair follicles and inhibit colonization by other microorganisms
What factors influence the quantity and type of resident flora? What type of bacteria predominate?
skin pH, moisture, fatty acids, other factors; gram positive bacteria predominate
What is the most common normal flora that is a gram negative rod? fungi?
gram neg rod: Acinetobacter spp; Fungi: Malassezia pachydermatis, Candida albicans
How are the transient flora of the skin acquired?
acquired from environment or mucosal membrane flora (remain for days to weeks)
What is Otitis Externa? What are the common agents in normal and abnormal ears?
inflammation of external ear canal, staph pseudintermidius, Staph felis, beta-hemolytic Strep spp, Malassezia pachydermatis
What agents are only found in abnormal ears?
gram negative bacteria: Pseudomonas aeruginosa, Escherichia coli, Proteus mirabilis, Klebsiella pneumoniae
What are the predisposing factors of Otitis externa?
breed, ear conformation, neoplasms, allergies, seborrhea, environment (moisture, trauma, foreign bodies, cleaning agents), other agents (Otodectes cynotis, demodex, sarcoptes, notoedres)
What are the clinical signs of otitis externa?
pruritus, head shaking, rubbing of ears against things, head shyness (pain); ear canal is reddened, often swollen, and may have moderate to large amounts of discharge, may have an odor
What are some more clinical signs of otitis externa?
attempts to scratch ear with ipsilateral hind paw, lesions on pinna and caudal to pinna on head, aural hematomas, severe cases may have head tilt
What is dry coffee ground-like debris typical of?
ear mite infection
What is waxy, greasy, yellow to tan discharge typical of?
ceruminous otitis; keratinization disorders, endocrine conditions, chronic hypersensitivity
What is moist brown discharge typical of?
staph and yeast infections
What is purulent creamy to yellow exudate typical of?
gram neg infections
How is otitis externa diagnosed?
otoscopic exam; cytological exam for bacteria, yeasts, mites; DQ stain for bacteria and fungi (>5 yeasts and/or >25 bacteria per high dry field)
What is a clinical sign of chronic otitis externa?
epidermal hyperplasia with thickening of pinna and narrowing or calcification of the ear canal
When is culture and sensitivity used?
cases that do not respond to current therapy or that may need systemic abx; take sample within the horizontal ear canal
Why is sensitivity testing usually not needed in cases of otitis externa?
concentrations of drugs used topically are much greater than what is present in the sensitivity discs
What is the treatment of otitis externa?
determine and eliminate and/or control predisposing factors; treat proper ear cleaning; topicals; systemic abx (middle ear infection or topicals can't be applied to ear)
What is the etiologic agent of Malassezia Dermatitis? morphology?
Malassezia pachydermatis; lipophilic yeast found as commensal on skin and mucocutaneous areas of dogs and cats
Where on the animals are the highest numbers of M pachydermatis found?
chin and lips, external ear canal, perianal regions, and dorsal interdigital areas
What are the clinical signs of infection with M pachydermatis?
pruritis, alopecia w/ erythema (reddened), seborrhea, hyperpigmentation, lichenification (thick and scaley), sour smell
Where on the animal are common affected areas?
interdigital, ventral neck, perianal, face, and axillary regions
What are the predisposing factors that allow proliferation of the yeast?
allergies, seborrhea, excessive bathing
What causes clinical signs to develop due to M pachydermatis?
allergic reaction to metabolic by-products of the yeast
How is infection with M pachydermatis diagnosed?
clincial signs, demonstration of yeast cells on skin scraping: small broad-based yeast cells
What is the therapy for M pachydermatis?
determine and treat predisposing factors; treat topically (shampoos or dips): miconazole, ketoconazole, clotrimazole, nystatin; consider oral azoles; *griseofulvin is ineffective
What is the zoonotic potential?
very low