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24 Cards in this Set

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What are the two types of incidence?
Cumulative and person-time
What is cumulative incidence also known as?
Risk
How do you calculate cumulative incidence?
Number of new cases of a disease occurring in a defined period of time
/
Number of people in the population at the beginning of the period
What does cumulative incidence measure?
How many new cases of a condition there are in a defined at-risk population over a specified period of time.

Requires a follow up study (cohort)
What does cumulative incidence not give?
Information about how each person's time at risk varies over the time period
How do you calculate person-time incidence?
Number of new cases of a disease occurring in a defined period of time
/
person-time risk
How is person-time incidence different from cumulative incidence?
The at-risk population is measured more accurately as it takes into account the fact that the people may drop out, migrate or die, or may only be intermittently exposed
Which is more accurate: Cumulative incidence or person-time incidence?
Person-time (think why!)

However it does require more resources and expenses.
When is the only time person-time incidence is not more accurate than cumulative incidence?
When the population remains completely stable - not common in epidemiological studies!
What is a 'person-year'?
One person being at risk of the outcome being measured for one year.

One person being at risk for six months would be half a person year
How do you calculate 'person-year'?
Multiply each person by time at risk the sum them all together.

This becomes the denominator
How would person-time incidence be expressed as a title?
'The incidence of HIV in Uganda is x per 100,000 person-years.
What is the variance of person-year called pack-year?
A pack year takes into account of how much exposure a person has to a particular factor.

E.g. 1 pack of cigarettes per day for 40 years = 40 pack-years
What are the two types of prevalence?
Point prevalence and period prevalence
What is point prevalence?
The number of existing cases of disease at one point in time
How do you calculate point prevalence?
Number of existing cases of a disease at one point in time
/
Population defined at the midpoint of the period
What is period prevalence?
The number of existing cases of disease during a defined period of time
Point prevalence includes people who were ill WAY before period of time
Therefore PP is higher than
How do you calculate period prevalence?
Number of existing cases of a disease during a defined period
/
Population defined at the midpoint of the period
Point prevalence includes people who were ill way before that period of time.
.
Over any given time, period prevalence is greater than _________. Because
incidence. Because period prevalence includes people who were ill way before the time, and the people presently ill.
Prevalence is typically expressed as...
...a percentage or number per 1000
Why measure prevalence? (3)
Used to find out how much of a disease burden there is on the population
Help in planning health services.
See whether a condition is getting more or less common
Why is the rate ratio calculated?
Calculated to compare the ratio of events occurring at any given point in time.
Rate Ratio = Incidence Rate 1/Incidence Rate 2