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15 Cards in this Set

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Helminths
(general)
Large, multicellular organisms
Sexual reproduction
Do NOT reproduce in host, therefore disease results from heavy infection
Eosinophilia
Helminths
(taxonomy)
Roundworms (nematodes)
Flatworms
1) Flukes (trematodes)
2) Tapeworms (cestodes)
Flukes
a.k.a. trematodes
Flatworms (like tapeworms)
Blind gut, leaf-shaped
Location! Location! Location!
(i.e. lung/liver/blood flukes, etc)
Flukes
(genera)
Paragonimus - Pulmonary (lung)
Fasciola/Clonorchis/Opisthorchis (liver)
Schitosoma (blood flukes, various species)
Fasciola/Clonorchis/Opisthorchis
Liver Flukes
Paragonimus
Lung Fluke
Schistosomiasis
(Life Cycle)
Humans shed eggs
Eggs hatch and freshwater snails
Recreational swimming, larvae burrow through skin
Larvae carried to lung, portal system or venous system (to urinary tract)
Mature, mate and produce eggs
Eggs MIGRATE through bowel/bladder and are excreted w/defecation or urination
Schitosomiasis
(Pathogenesis)
BASED ON HOST IMMUNE RESPONSE
3 stages
1) Dermatitis (pruritic, papular rash) w/entry
2) Acute: systemic allergic rxn w/egg production (2-8 weeks poost infection)
3) Chronic: trapped eggs, granulomas (w/resulting hepatic and urinary complications)
Tapeworms
(Cestodes)
2 stages:
1) Adult tapeworm (scolex and proglottids)
2) Multicellular larvae - cysts
Tapeworms
(life cycle)
Ingest cyst
Adult worm (scolex + proglottids)
Occasionally shed proglottids/eggs w/feces
Eggs to larvae (inside/outside animal?)
Animals: larvae to tissue, form cysts
Cysticercosis
Cysts in Humans!
Neurocystocercosis (cysts in CNS)
Results from ingestion of EGGS
(normally, people ingest cysts and get the adult tapeworm - but if we eat eggs, you can develop cysts yourself!)
Why get cysticercosis vs. adult tapeworm?
It depends on what stage youo ingest!
If bad meat, you're eating the cyst - will form the adult
If eggs (from poop), you'll have maturing/migrating larvae that will form cysts in YOU!
Neurocystocercosis
Taenia solium
Larvae infect CNS and form cysts
Viable cysts - asymptomatic or obstructive hydrocephalus
Dead cysts - inflammatory response - SYMPTOMS
Echinococcus
Hydatid Disease
Dogs = definitive host (house adult worms)
Sheep/rodents = intermediate host (ingest eggs/larvae when grazing)
Dogs eat animal meat (w/cysts) and cycle continues
Hydatid Disease
Echnococcus
HUGE cysts that are teaming w/larvae (very promiscuouos - therefore must be EXTREMELY CAREFUL w/aspiration)