Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
18 Cards in this Set
- Front
- Back
|
Picornaviridae
|
Pico = Small
(+) (P, for positive) ssRNA Non-enveloped |
|
|
Picornaviridae
(major genera) |
Think "Little PHK-ER"
Parechovirus Hepatovirus Kobuvirus Enterovirus Rhinovirus |
|
|
Enterovirus
|
Of Picornaviridae (Little PHK-ERs)
Tells you they're non-enveloped, small, ssRNA PEECABoo (the types) Poliovirus Echovirus Enterovirus Coxsackie, A and B |
|
|
Pathogenesis
(Enterovirus, Hepatovirus, Parechovirus) |
Surface cytocidal
Systemic cytocidal (viremia and disseminated infection, organ specific disease) |
|
|
Most common cause of acute Aseptic Meningitis?
|
Enterovirus
Symptoms: fever, severe headache, nausea/vomiting, stiff neck, blood "viral pattern" (absent leukocytosis) |
|
|
What is a blood viral pattern?
|
Normal counts or lymphocytosis
|
|
|
Major Syndromes attributed to Enterovirus, Hepatovirus and Parechovirus Infection
(FEERD CHAMPP) |
Aseptic Meningitis
Paralytic poliomyelitis Myocarditis Febrile exanthem/enanthem Herpangina Pleurodynia Conjunctivitis Respiratory Disease |
|
|
Coxsackie B
|
Myocardities and Pleurodynia
|
|
|
Coxsackie A
|
Febrile exanthem and herpangina (think rashes all over)
|
|
|
Febrile Exanthem/Enanthem
|
Due to Coxsackie A/ECHO
|
|
|
Do enteroviruses cause diarrhea?
|
Generally, their infection is ASYMPTOMATIC. You MUST KNOW THAT Rotavirus and Enteric Adenoviruses are the leading agents of viral gastroenteritis
|
|
|
Epidemiology of Enteroviruses
|
WARMER MONTHS
Within families Food/water vehicle |
|
|
Hepatovirus (Hepatitis A Virus)
|
It's a "Little PHK-ER"
Part of the picornaviridae (tells you they're small, non-enveloped, (+) ssRNA) Fecal-oral route w/systemic spread to Liver (as a systemic infection, tells you that you'll have a long incubation period) |
|
|
Hepatitis A Virus
(Pathogenesis) |
Fecal-Oral Route
Ingested w/Systemic spread to Liver (long incubation period) Infection may be asymptomatic, symptomatic (non-icteric or icteric) |
|
|
Hepatitis A Virus
(Epidemiology) |
Endemic in all countries
Vaccinations are effective as suggested in high-risk groups in the developed world |
|
|
Rhinovirus
|
It's a "Little PHKER"
Tells you it's of Picorniviridae (small, (+) ssRNA, and non-enveloped) Most common cause of the common cold (URI) |
|
|
Clinical symptoms of the common cold
|
Sneezing, nasal obstruction and discharge
|
|
|
Rhinovirus
(epidemiology) |
Fall/Spring
VERY COMMON Infections TONS of serotypes (so it makes vaccination improbable) |
