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18 Cards in this Set

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Picornaviridae
Pico = Small
(+) (P, for positive) ssRNA
Non-enveloped
Picornaviridae
(major genera)
Think "Little PHK-ER"
Parechovirus
Hepatovirus
Kobuvirus
Enterovirus
Rhinovirus
Enterovirus
Of Picornaviridae (Little PHK-ERs)
Tells you they're non-enveloped, small, ssRNA
PEECABoo (the types)
Poliovirus
Echovirus
Enterovirus
Coxsackie, A and B
Pathogenesis
(Enterovirus, Hepatovirus, Parechovirus)
Surface cytocidal
Systemic cytocidal (viremia and disseminated infection, organ specific disease)
Most common cause of acute Aseptic Meningitis?
Enterovirus
Symptoms: fever, severe headache, nausea/vomiting, stiff neck, blood "viral pattern" (absent leukocytosis)
What is a blood viral pattern?
Normal counts or lymphocytosis
Major Syndromes attributed to Enterovirus, Hepatovirus and Parechovirus Infection
(FEERD CHAMPP)
Aseptic Meningitis
Paralytic poliomyelitis
Myocarditis
Febrile exanthem/enanthem
Herpangina
Pleurodynia
Conjunctivitis
Respiratory Disease
Coxsackie B
Myocardities and Pleurodynia
Coxsackie A
Febrile exanthem and herpangina (think rashes all over)
Febrile Exanthem/Enanthem
Due to Coxsackie A/ECHO
Do enteroviruses cause diarrhea?
Generally, their infection is ASYMPTOMATIC. You MUST KNOW THAT Rotavirus and Enteric Adenoviruses are the leading agents of viral gastroenteritis
Epidemiology of Enteroviruses
WARMER MONTHS
Within families
Food/water vehicle
Hepatovirus (Hepatitis A Virus)
It's a "Little PHK-ER"
Part of the picornaviridae (tells you they're small, non-enveloped, (+) ssRNA)
Fecal-oral route w/systemic spread to Liver (as a systemic infection, tells you that you'll have a long incubation period)
Hepatitis A Virus
(Pathogenesis)
Fecal-Oral Route
Ingested w/Systemic spread to Liver (long incubation period)
Infection may be asymptomatic, symptomatic (non-icteric or icteric)
Hepatitis A Virus
(Epidemiology)
Endemic in all countries
Vaccinations are effective as suggested in high-risk groups in the developed world
Rhinovirus
It's a "Little PHKER"
Tells you it's of Picorniviridae (small, (+) ssRNA, and non-enveloped)
Most common cause of the common cold (URI)
Clinical symptoms of the common cold
Sneezing, nasal obstruction and discharge
Rhinovirus
(epidemiology)
Fall/Spring
VERY COMMON Infections
TONS of serotypes (so it makes vaccination improbable)