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324 Cards in this Set

  • Front
  • Back
What things cause lower GI bleeds?
diverticular disease, angiodysplasia, hemorrhoids, cancer, IBD, diarrhea
If you see bright red blood per rectum, is it upper or lower GI?
it could be both!
What are the treatments for peptic ulcer disease?
1st- acid supression
2nd- endoscopic cogaulation/clips
3rd- surgery cut it out
What is the presentation of mallory weiss?
hx of non bloody vomit....THEN later blood streaks
how likely is it a person with a bleeding esophageal varice will have it stop on its own?
about 50%
how likely is it for esophageal varacies to bleed again later?
very likely, usually occurs within the first few days, but can be up to 6 weeks
How do you restore fluids into a person who has serious blood loss?**
two large bore IV's in the periphery, giving normal sailne and blood products
What is the main drug given to treat esophageal varcies?**
Octerotide**

this decreases intravaraceal pressure within seconds
what is the DEFINITIVE treatment for active variceal hemorrhage***
endoscopy- band ligation
what is the most common cause of lower GI bleeding***?
diverticulosis
What type of vessels are involved in agniodysplasia?
VENOUS ones
What MUST be done to evaluate signs of colorectal cancer?
full colonoscopy
What are the signs of LEFT sided colon cancers?
change in bowel habits (poop is solid by then, so can be obstructed)
What are the signs of RIGHT sided colon cancers?
blood loss, fatigue, anemia
What is the most common cause of small bowel obstruction?
surgical adhesions
how do you diagnose small bowel obstruction?
plain film, showing air fluid levels (sitting up)

CT is used to delineate better
What is the treatment for small bowel obstruction
NPO
IV
antiemetics

SURGERY**
What is the MOST common cause of large bowel obstruction?
malignancies
What NEVER causes large bowel obstructions?
surgical adhesions
what causes cecal volvulus?
congenital peritoneum defect
who gets sigmoid volvulus?
older disabled people in instiutions
how do you BEST treat volvulus?
surgery

or ram a sigmoidoscope through it (beware the poo coming out!)
What causes diverticulosis?
muscular hypertrophy of the colonic wall
What part of the colon is most likely to have diverticulosis
the sigmoid colon
does the bleeding usually stop on its own in diverticulosis?
yes it does is 75-95% of cases
in diverticulosis, what type of vessel ends up bleeding (think of this in opposition of angiodysplasia)
ARTERIES bleed here
what part of the colon does diverticular bleeding usually occur?
on the RIGHT side
what part of the colon does diverticulosis usually occur?
the LEFT colon
what is the most common complication of diverticular disease?
diverticulITIS - infected diverticula
What is the required diagnostic test for rectal/anal abscess?
CT of pelvis with contrast
What is the treatment for rectal/anal abscess?
PROMPT surgery
What complication occurs in 1/2 of all anal abscess pts?
a chronic fistula
What is an anal fistual?
this connects the anal canal with the skin, and is lined with epithelium and graunlation tissue
what is the definitive treatment for anal fistulas?
surgery
what is a type 1 rectal prolapse?
only the mucosa comes out- not much protrusion
what is a type 2 rectal prolapse?
your whole ass falls out- full thickness
How do you treat rectal prolapse?
manual reduction
what typically causes blunt abdominal trauma?
car accidents
what usually gets damaged in blunt abdominal trauma?
the kidney is #1

(others are spleen and liver)
What may be the initial presentation of blunt abdominal trauma?
may have NO complaints
What is the most common sign of blunt abdominal trauma?
hypotension- from bleeding out

Seat belt sign- a seat belt bruise
what is the best exam for finding blunt abdominal trauma?
FAST exam- focused assesment with sonography for trauma
How do you determine a blunt abdominal trauma bleed if the CT cant find it?
diagnostic peritoneal lavage - invasive
what is the most common cause of esophageal perforation?
medical instruments or paraesophageal surgery
whats the most commonly ingested foreign body?
coins
what is the first test for foreign body? (two angles)
CXR- AP for esophagus

Lateral projection for trachea**
what do you examine first with foreign body?
airway and breathing
why is eating flat batteries so bad?
these will cause necrosis of the stomach
if you stuff drugs in your butt, why is this more dangerous than carefully wrapping them?
they can get into your system and kill you
before what gestational age is a pregnancy called an embryo?
before 10 weeks
what is the most important risk factor for spontaneous abortion?
advanced maternal age
what are the signs of threatened abortion?
bleeding through a closed OS in the first 1/2 of pregnancy.

as long as fetal cardiac activity is cool- babys fine
what is an incomplete abortion?
after 12 weeks, most of the bits come out, but not parts of the placenta
What are the classical signs of GERD?
heartburn- postprandial/nocuturnal
aggivated by change in position (lying down)

prompt relief by antacids
What is the atypical presentation of GERD?
laryngitis
hoarsness
throat cleaning
chronic cough
asthma
What are the complications of GERD?
barretts
ulcer
stricture
What are the 'alarm symptoms' for GERD (and its progression)
older than 55
anemia
dysphagia
respiratory problems
early satiety
weight loss
persistant symptoms despite treatment
What type of esophageal cancer is becoming alot more common?
adenocarcinoma
What is the BEST first phase treatments for GERD?
lifestyle changes!!

stop smoking
weight loss
elevate head of bed
no food/drink after 6pm
what is the geneotype for celiac disease?
DQ2 and DQ8
What is needed for a diagnosis of celiac disease?
tissue transgluatminase anitbodies

villous artrophy
What are the GI symptoms of celiac disease?
bulky foul smelling stool
pain
flatulence
(basically malabsoprtion signs)
What diseases can manifest from celiac disease related to fat soluble vitamin malabsoprtion (AEDK)
night blindness
rickets, osteoporosis
peripheral neruopathy
excessive bleeding
anemia
What are some of the external signs of Celiac disease?
Infertility
dermatitis herpetiformis
What diseases have an increased mortality with Celiac disease?
adenocarinoma
t- cell lymphomas
What is the treatment of Celiac disease?
strictly delete the wheat
what thickness of inflammation does crohns have?
this is full thickness
What are the hallmarks of crohns?
focal areas of ulceration, skip lesions

often has structures, fistulas
What are the diagnostic studies for crohns?**
small bowel capsule endoscopy

CT or MRI enterography

looks for "String Sign"**
What are the colonoscopy hallmarks for crohns?
cobble stone appearance
what are the colonoscopy hallmarks for ulcerative colitis?
crypt abscesses
pseduopolyps
continuious involvement NO skips
what is the major complication of ulcerative colitis?
cancer (after about 8-10 years of UC)

and maybe toxic megacolon
What are the extra intestinal complications of Inflammatory Bowel Disease***
uveitis
erythema nodosmu
pyoderma gangrenosum
arthritis
apthous ulcers
primary sclerosing colangitis (seen with UC)**
what is irritable bowel syndrome?
abdominal pain and altered bowel habits in the absence of any organic cause
What are the ROME III diagnostic criteria for irritable bowel syndrome?
abdominal pain, at leas 3 days per month for last 3 months

improves with defecation
onset associated with change in frequency
onest associated with change in form of poo
What are the predominant symptoms of irritable bowel syndrome?
constipation
diarrhea
alternating of constipation and diarrhea
abdominal pain
bloating
Who usually gets irritable bowel syndrome?
young women
What bugs usually cause post infectious irritable bowel syndrome
campylobacter and E coli
What are the red flags assocaited with irritable bowel syndrome?
unintentional weight loss
onset in older people
blood loss labs
bleeding
What are the route causes of irritable bowel syndrome?
altered GI motility
visercal hypersensitivity
microscopic inflammation
post infection
psychosocial
What do people with psychosocial irritable bowel syndrome present with?
anxiety, depression, phobias, somatization

Hx of abuse
What is the major concern of Long term ulcerative colitis?
colon cancer
what is the major difference between regional enteritis and ulcerative colitis?
regional enteritis is full thickness, while UC is only mucosa
What is the normal range for AST
10-40
What is the normal range for ALT
15-40
What is the normal range for alkaline phosphatase
25-165
what is the normal range for total bilirubin?
0.5-1.0
What things increase unconjugated bilirubin production
hemolysis, ineffective erythropoiesis, muscle injury, hematomas
what things increase conjugated bilirubin in the blood?
liver disease or obstruction
What doe elevated GGT a sensitive indicator of?
hepatobiliary source of elevated alkaline phosphatase- as in chronic drinking
What clotting measurement is prolonged in liver failure?**
Prothrombin time
What can be conjugated bilirubin levels be used as a measure of?
these can be used as a prognostic measurement depending on the severity of their elevation
What labs are very elevated with Cholestatis/ infiltrative liver disease?
alkaline phosphatse and GGT are very high
What labs are very elecated with hepatocellular disease
ALT and AST are very elevated
What two types of hepatitis do NOT cause chronic infection?
hep A and E
What two types of hepatitis are from feces?
hep A and E
What are the serum signs of hepatitis A infection?
initially high ALT levels, then increased anti-HAV
how do you get hepatitis A?
close personal contact
contaminated food/water
blood exposure
what is the course of hep A?
self limited
Who should get Hep A vaccine
everyone
If you get ONLY the hepatitis vaccine, what type of antibodies do you make?
ONLY anti-HBs (hep b surface)
If you get immunized against hep B, but still get infected, what antibodies do you make?
anti-HBs (surface) and anti-HBc (Core)
what age do you get hep B, and have the greatest risk of chronic illness?
under 5
What percent of people get a chronic hep C infection?
60-85%
What can be a severe consequence of long term Hep C infection?
hepatocellular carcinoma
What things cause faster hep C progression
booze
over 40 @ time of infection
HIV
While in both chronic and acute HCV infection anti HCV will increase over time. what two factors will spike again later with chronic HCV infection?
HCV RNA and ALT

anti-HCV will stay high after the first infection no matter what
What are the causes of HCV infection?
IV drugs
transfusion
occupational exposure
latrogenic
sex
How effective is occupation needle stick at transmitting HCV?
low, about 1.8%
What is the treatment for HCV?
Ribavirin + something else
What MUST you have first in order to get hepatitis D?
hep B
How do you get hep D?
IV drugs and sex
What is the treatment for hepatitis A?
supportive care
what kind of hepatitis do you get from tattoos?
HCV
What is the first sign of alcoholic liver damage (from a normal liver)
a fatty liver change
Do most pts who abuse alcohol progress to liver injury?
nope only a small percent
What are the lab ratios for alcoholic fatty liver?**
AST > ALT**

typically asymptomatic
What are the lab ratios for NONalcoholic fatty liver?**
ALT> AST **
what are the causes of nonalcoholic fatty liver?
obesity
massive weight loss
TPN
diabetes
What is the presentation of alcoholic hepatitis?
anorexia
modest fever
hepatomegaly
jaundice
dark urine
clay colored stools
While in alcoholic hepatitis, AST>ALT, what level is neither one much higher than?
neither is much greater than 200
what really improves survival in alcoholic cirrhosis?
abstinence
what are the physical findings in alcoholic cirrhosis?
temporal wasting
spider angiomata
jaundice
firm liver edge
palpable spleen
ascities
asterixis
What are the liver function tests like for Liver Cirrhosis?
slightly up ALT/AST, with VERY HIGH AP and GGT
should you do elective surgery on a person with cirrhosis?**
no
what is the only defined treatment for cirrhosis?
liver transplant
what is primary biliary cirrhosis?
an autoimmune liver disease that generally affects middle aged women
What are the typical signs of primary biliary cirrhosis?
fatigue and pruritis (tired itchy people)

RUQ pain

Anorexia

jaundice
What are the skin signs of primary biliary cirrhosis?
hyperpigmentation

xanthomas
what are the abdominal signs of primary biliary cirrhosis?
striking hepatomegaly
What are the serologic hallmarks of primary biliary cirrhosis?- key**
elevated AP and GGTP

AMA (anti-mitochondiral antibodies)*** DIAGNOSTIC
What is the best treatment for primary biliary cirrhosis?
ursodeoxycholic acid
What is the definition of acute liver failure?
onset of hepatic encephalopahy either:
-less than 8 weeks after onset of liver disease in previously healthy liver
or- less than 2 weeks after jaundice onset in person with underlying disease
What are the main causes of acute liver failure?
toxins/drugs

hep B

vascular infarcts
What are the MAIN complications of acute liver failure?
encephalopathy
cerebral edema (due to high NH4 levels)

lactic acidosis, renal faiure
what is the most common manifestation of liver decompensation?
ascities
what is the prognosis of ascities?
poor
what is the recurrence rate of spontaneous bacterial peritonitis?
about 70% at one year
what is the major danger associated wtih transjugular intrahepatic protosystemic shunt?
major risk of hepatic encephalopathy as NH4 now directly enters the blood stream from the gut
what usually causes chronic pancreatitis?
alcoholism
What is mild acute pancreatitis associated with?
minimal organ damage and uneventful recovery
what is severe acute pancreatitis associated with?
necrosis, organ failure, and death
what are the most common causes of pancreatitis ?
gallstones and alcohol abuse

but in 10-25% NO cause is found
What is the etiology mnemonic for things that cause pancreatitis ?
Trauma
Hypertriglyceridermia
Idiopathic
Scorpion bites

(is)

Biliary
Alcohol
Drugs
what race gets more pancreatitis ?
blacks
what disease has a very high rate of pancreatitis
AIDS
What enzymes get activated to cause pancreatitis
trypsinogen, zymogens, and lipase
what is the typical clinical presentation of pancreatitis
sudden onset epigastric abdominal pain,
radiating to back and flanks.
usually dull constant and boring
*improves my leaning forward*
what are the lab tests for pancreatitis
amylase and lipase
What test suggest gallstone pancreatitis?
ALT greater than 150
what test suggest severe necrotizing pancreatitis?
HCT greater than 47%
What CRP value indicates severe pancreatitis
CRP above 150
What are the principles of treatment for acute pancreatitis ?**
Fluid replacement**
when does infection occur with pancreatitis ?
usually in the second week of pancreatic necrosis
What is the treatment for infected pancreatitis necrosis?**
Fine needle aspiration
what is chronic pancreatitis ?
inflammation, fibrosis, and cell loss due to ductal obstruction from strictures due to a proteinaceous plug
what are the signs of chronic pancreatitis ?
chronic intermittent abdominal pain radiating to back
N/V
steatorrhea
What is the most common tracheoesophagela fistual?
esophageal atresa, with a distal tracheoesophageal fistual
What is the defect associated with esophageal atresia? (and its mnemonic)
VACTERL

Vertebral anomalies
Anal atresia
Cardiac anomalies
TEf
Renal anomalies
Limb anomalies
what is the classic lab finding in hypertrophic pyloric stenosis?
hypochloremic metabolic alkalosis (you puke up all your acid= alkalosis)
what xray sign is used to diagnose pyloric sphincter
String sign
what is the character of functional abdominal pain?
daily pain not associated with meals or relived by defection

often associated with anxiety and perfectionism
what are the warning signs with recurrent abdominal pain?
vomiting
fever
growth failure
pain awakening kid from sleep
weight loss
location away from periumbilical region
blood in stool/emesis
what is given to manage IBS symptomes?
fiber supplements
what is the classic late finding in intussusception?
currant jelly stools
what is the most common location for intussusception in kids?
ileocolonic
what is the clinical manifestations of intussusception?
suddent onset crampy abdominal main- infants knees draw up, cries out, exhibits pallor with a colicky pattern every 15-20 min

refuses feedings
What is the unexpected clinical feature of intussusception?
Lethargy**
What is the best way to treat intussusception?
contrast enema

fluid resuscitation
What are the most common food causes of anaphylaxis in kids in descending order?
peanuts (most common)
tree nuts
milk
eggs
fish
shellfish
seeds
fruits
grains
While most childhood allergies to food are outgrown, which are not?
peanuts, tree nuts, fish, shellfish
When must liver disease in a kid be suspected?
mild jaundice, but dark colored urine and light colored stools
What does green onion sign associated with?
obstructiong ureterocele
should you be worried about UTI's in children?
yes you should, because they dont usually get them
Should you be worried about recurrent UTI's in adults?
yes- suspect Stasis or obstruction
What does loss of a psoas shadow mean?
retroperitoneal pathology on that side
What does loss of BOTH psoas shadows mean?
ascities
What should you be worried of if the ureter runs more midline, rather than lateral?
an obstructing mass
Is hydronephorsis ok in pregnancy?
yes it i- goes away afterwards
How do you recognize neovasuclar tumors of the kidneys?
look for new branching arteries, and smudging on arteriograms
How do you kill neovascular tumors in the kidney?
embolize them
What is the presentation of renal carcinoma?
gross hematuria

vauge upper abdominal pain

fatigue, weight loss, anemia (typical caner signs)

most are found by chance..
How good is the survival of renal cell carcinoma?
pretty danm good until it breaks out of the capsule (stages 1-2)
Where are the common metastasis sites of Renal carcinoma?*
to the BONE*
What is the best treatment for renal cell carcinoma?
take the kidney out
What will you automatically have after a 50 pack year hx of smoking?
GU cancer
What is the sign of retroperiotenal fibrosis?
medial deviation of mid ureters
What are the main causes of retroperiotenal fibrosis?
idiopathic

methysergide

cancers
why is it important to always retract the foreskin?
to look for cancers
What are the four indications to insert a foley cath?
relieve bladder distension

collect uncontaminated urine

monitor urine output

bladder tests (cytogram/urodynamics)
what are the three contraindications for foley catheters?
blood from urethra or urethral disruption

acute prostatitis

Hx of urethral strictures
What is the golden rule of inflating foley cath?
dont inflate unless you see urine first
what is the chirstmas tree bladder a sign of?
neruogenic bladder
What is the most significant symptom of obstructive prostatic hyperplasia?
Nocturia 2-3 times a nigh
what shape do the ureters make in obstructive benign prostate hyperplasia ?
a J shape
What shape does the bladder take on in obstructive benign prostate hyperplasia?
trabeculation
What is the gold standard treatment for obstructive benign prostate hyperplasia?
TURP- transurethral resectoscope prostetomy
what is Post TURP syndrome?
the irrigation fluids used in TURP have low sodium, so this causes water intoxication in the pt.

N/V/CHF

tx diruetics
When is it best to treat post TURP syndrome?
before acute retention occurs
What are the less invasive treatments of obstructive benign prostate hyperplasia?
Urolume stent

green light laser

various ablation techiques
where are the three common locations for kidney stones?
renal pelvis

where it crosses the pelvis

going into the bladder
How common is recurrence of kidney stones?
about 50%
What bug causes staghorn stones, or recurrent kidney stones?
Proteus
What are the inducations of uroogical intervention with urinary stones?
intractable pain
high grade obstruction
What is the BEST radiographic technique for diagnosing urolithiasis?
unenhanced helical computed tomorpgrahy (CT)
What is the best way to remove simple renal caculi?
shock wave lithotripsy
What is the best treatment for complex renal stones?
percutaneous nephrostomy
When is ureterocopy the best treatment for small stones?
shock wave failes
pregnant pt
obese
pt is a bleeder
What are the four types of incontinenece?
Stress

Urge (sudden need/loss of bladder control)

Overflow (neuro)
Mixed
How many people have stress urinary incontinence?
13 million people
What part of the urinary system is the "zone of continence"?
the proximal 2/3rd of urethra and bladder neck
What history suggests Stress incontinence
multiparous women, pelvic surgery, activity related
What history suggest urge incontinence?
UTI, new Rx, hematuria, CVA
What history suggest overflow incontinence?
diabetic, never feels empty, back problems, surgery
does a cystocele cause incontinence ?
nope
does a cystourethrocele mean incontinence?
yes it does
What does the marshall test for incontinence do?
this looks for failure of the zone of continence
What do young men with ED need a work up for?
cardiovascular eval, maybe have severe asymptomatic coronary artery disease
what test is given before giving viagra?
two flights of stairs test
what is THE BEST treatment for ED?
inflatable penile implants- 98% couples satisfaction
does prostate cancer cause bone mets?
Yes, but they are osteoBLASTIC

unlike renal cell- which is osteolytic
What are the symptoms of prostate cancer?
same as obstructive benign prostate hyperplasia

increased PSA velocity, Low% free PSA is bad
What are the signs of bladder cancer?
gross hematuria

change in voiding pattern
how do you treat superficial bladder cancer?
tranurethral resection of tumor, with lots of check ups
what is the treatment for invasive bladder cancer?
radical cystectomy
Where does testicular cancer metastasis to?
lung, liver, bone
What is the most common type of testicular cancer?
pure seminoma
What is the treatment for a pure seminoma?
xray therapy
what nodes does testes cancer go to first?
retroperitoneal lymph nodes
What are the risk factors for penile cancer?
uncircumcised
VD
HPV
Smoking
What are the signs of fourniers gangrene?
dead/discolored tissue on scrotom

fever/drosiness

genital pain and redness

odor
What is the Tx for fourniers gangrene?
CUT IT ALL OUT
What is the BEST treatment for internal hemorrhoids?
rubber band ligation

dont pack the anal canal.
What is a pilonidal cyst?
a cyst or abscess near or in the upper intergluteal cleft- usually has hair and skin debris in it
who gets pilonidal cysts?
hairy butted men- with prolonged sitting
how do you treat pilonidal cyst
BIG time complete excision - and dont close it just let it fill in from the outside
what kind of hernia produces bowel perforation without obstruction?
richter hernia
What is the risk of having anesthesia withing 3 months of an MI?
risk of re-infarction
what is an acceptable pre-op Hgb in healthy people
8gms
What is Newhoffs law?
if you dont get out of bed, you dont get any pain meds
what do hiccups indicate post surgery?
that its too early for oral intake of foods
how do you fix post of ileus due to gastric atony?
an N.G feeding tube
What is the most likely cause of fever post op in the first 24-48?
atelectasis
how are HgB and Hct affected by acute bleeding?
they are misleadingly high
What is the problem with the jejunoileal bypass?
LOTS of metabolic issues
What is the most effective weight loss surgery?
roux en Y subtotal gastrectomy
how much per cent excess weight is lost with roux en Y subtotal gastectormy?
60-80%
What disease (other than being fat) is often cured with gastric bypass surgery?
type 2 DM
what part of the history does a living will and religious restriction go into?
Social Hx
Who should not be given lactated ringers solution?
pts with renal insufficiency
What is nonspecific abdominal pain?
no organic cause found
what is the most likely origin of rapid onset severe abdominal pain?
vascular, rupture, stones, cysts
What is the most likely origin of slow insidious onset abdominal pain?
inflammatory processes
What is the classic finding for mesenteric ischemia or pancratitis?
pain out of proportion to physical findings
what kind of abdominal pain is relived with eating?
ulcers
what kind of abdominal pain is worse after eating
biliary colic
what xray position is best for looking for free air under the diaphragm (as in a perforation)
sitting upright xray
What are the major risks of causes gall stones?
native american woman.
fat
crohns disease
drugs
What are the 5 "F"s of gallstones?
Fat
Female
forty
fertile
fiar skin
What type of gallstone is usually found in adults, as a solitary stone?
cholesterol stones
what type of gallstone is usually found in kids, as multiple stones?
pigmented stones

due to high unconjugated bilirubin
What is the pain of gallstones like?
intense dull pressure in the RUQ
intolerance of fatty foods, nausea, vomiting, flatuence
What does the diagnosis change to if gallstone pain lasts longer than 6 hours?
this is the onset of cholecystitis (inflammation)
What is the normal ejection fraction for the gallbladder when adminstering CCK?
at least 50% is normal
what NSAID has been shown to stop the progression of gallstones to cholecystitis?
IM diclofenac
What is the best therapy for symptomatic gallstones?
cut it out
What is the best therapy for asymptomatic gallstones?
observation and NO surgery
what is the most common complication of laparoscopic cholecystectomy?
common bile duct injury
What kind of pt gets oral bile acids to dissolve stones, rather than surgery?
functional gallbladder
small stones
-and have a comorbid condition that prevents surgery
when do you hospitalize a pt with gallstones?
intractable pain

evidence of cholecystitis, cholangitis, pancreatitis, choledocholithiasis (stones in bile duct)
what is cholecystitis?
this is acute inflammation of the gallbaldder, usually caused by migration of gall stones into the cystic duct
What are the main infective organisms seen in acute cholecystitis?
E coli, klebsiella, enterococci
What is the KEY sign for acute cholecystitis?
murphy's sign

hand under ribs, breathing in makes gallbladder poke hand and hurt
what is the initial test for cholecystitis, even though its not very sensitive?
ultrasound
What are the ultrasound signs of cholecystitis?
thicked gallbladder wall, distended gallbladder and a cystic duct with stones in it
what is a positive HIDA scan result like?
the gallbladder is NOT visualized, because the cystic duct is blocked

only see isotope in biliary tree and duodenum
What is the treatment of acute cholecystitis?
NG tube, and early cholecystectomy- dont wait for inflammation to subside
what is the most common complication of acute cholecystitis?
gangrene
what causes ephysematous cholecystitis?
secondary infection of the gallbladder with gas forming organisms (clostridum)

shows as crepitus of abdominal wall next to gallbladder
what are the signs of choledocholithiasis (common bile duct stone)
Hx colicky pain, but sudden onset severe RUQ pain.

N/V/ cholangitis

obstructive jaundice** (elevated GGT)
What is charcot triad?
what disease does it indicate?
RUQ pain
Jaundice and fever
rigors

this indicates acute cholangitis- infection of bile duct
what is an antalgic gait?
compensatory to pain, shorter Stance phase on hurt leg
what is a steppage gait?
loss of ability to dorsiflex the foot, swing leg to swing foot up in air
What is equinus gait?
toe walking- due to cerebral palsy, tight achilles, hurt heal
is a trendelenberg gait painful?
no it is not
What is the most common cause of antalgic gait in a toddler?
toddlers fracture (a spiral fracture of the tibia)
what is the most common cause of trendelenberg gait in a toddler?
cerebreal palsy
What is the most common cause of antalgic gait in kids 4-10?
legg calve perthe disease
What is the most common cause of antalgic gait in kids 11 yrs+
SCFE
What should be suspected with bone pain at rest?
tumors!
What are the Xray angles used for a limping kid?
AP, Lateral, and FROG LEG**
What lab tests should be ordered for a limping kid?
CBC, C reactive protein, cultures

to rule out infectious causes
what is the typical pt of Legg Calve Perthes disease?
idiopathic avasular necrosis of femoral head
BOYS, 5-9, kids who are lower percentiles of height for age
What makes an LCP limp worse?
activity, limp worse at end of day
what range of motion is limited in LCP?
abduction of the hip is limited on involved side
What does the leg musculature look like in LCP?
the affected leg will atrophy a bit
what is the xray sign for LCP?
crescent sign
What type of fracture is a slipped cap femoral epiphysis?
a salter harris type 1
What is the most sensitive and specific physical finding for SCFE?
loss of hip internal rotation
what is the xray finding for SCFE?
a positive klein line
What is the most likely cause of transient synovitis?
recent URI
what are the sings of transient synovitis?
pt awakens with a limp and refuses to walk. localized pain to groin or proximal thigh
what is the Tx of transient synovitis?
NSIADS and bed rest
What is the most common agent in septic arthritis?
staph aureus
what is the presentation of growing pains?
mild to moderate pain, more noticeable during rest

no limp during day.
What is the presentation of a DKA pt?
Kusmmal breathing
fruity odor to breath
altered mental status
What are the defining labs for DKA?
glucose above 300
ketonemia above 1:2
acidemia lower than 7.30
How can the white count be affected in DKA?
it may be elevated by stress alone
what happens to potassium levels in DKA upon treatment with insulin?
they will TANK, must give KCL
What is the FIRST treatment of DKA?
give them fluid!!

this will help with the acidosis AND the blood glucose levels
After blood sugar drops with fluids in DKA tx, what do you give them next?
add dextrose, as you dont want to tank their blood sugars
What is the first thing we do in hyperosmolar hyperglycemic state?
give them fluids!
what is hyperosmloar hyperglycemic state?
lack of insulin, but not enough to cause DKA-

ends up causing neurological deficits
how is serum sodium affected in DKA?
it is falsely lowered by the high sugars
what is used to clear the ketones and fatty acids in DKA?
insulin and fluids only
What things are required for internal validity?
random assignment

groups similar at start

Similar length of follow up

complete follow up

were pts analyzed in the same groups as which they were put into?

were the people reading the results blind to treatment groups?
What is a P value?
a measure of how likely that a difference between groups in non random
are pts who never actually received their assigned treatment excluded from analyses?
No they are not
How do you compute absolute risk
this is risk without therapy. so what % of control group had a bad outcome
how do you compute absolute risk reduction
this is the risk of NOT having treatment, minus the risk of having treatment
how do you compute relative risk
risk with therapy/ risk without therapy

if less than 1, treatment is good
how do you compute NNT?
this is 1/over the absolute risk reduction
What is a confidence interval
this is an interval that the realtive risk should fall within in order for it to be a good test
What is an intention to treat protocol
this puts all people into the original group they were assigned, regardless of what treatment they ended up getting