Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
24 Cards in this Set
- Front
- Back
|
HBV incidence is highest in age group ___
|
20-29
|
|
|
HDV is a ___ virus which requires previous infection with ___
|
RNA
HBV |
|
|
most common HBV genotype in USA
in mediterranean |
A
D |
|
|
5 phases of chronic HBV
|
immune tolerance
immune clearance inactive HBsAg carrier resolution reactivation |
|
|
ALT can be elevated in ___ phases of chronic HBV
|
1
2 5 |
|
|
liver histology shows active disease in phases ___
|
1
2 5 |
|
|
HBV DNA is present in phases ___. It is high in phases ___ and moderate in phase ___.
|
1
2 5 1 2 5 |
|
|
moderate level of HBV DNA is >___ IU/ml. high level is > ___.
|
2000
20000 |
|
|
HBeAg is present in phases ___.
|
1
2 |
|
|
HBsAg is present in phases ___ for ___ months.
|
1
2 3 5 6 |
|
|
HBeAg is a cleavage product of ___
|
HBcAg
|
|
|
HBsAg in serum means ___
|
ongoing infection
|
|
|
HBeAg in serum means ___
|
ongoing viral replication
|
|
|
HBcAg in serum means ___
|
impossible-only in hepatocytes
|
|
|
anti-HBs in serum means either ___ or ___
|
immunized
infected and recovered |
|
|
IgM anti HBc means ___ (2)
|
acute infection
reactivation |
|
|
IgG anti HBe means ___ or ___
|
post infection
mutant ongoing infection |
|
|
___ hepatocyte is characteristic of HBV. the ER is full of ___.
|
ground glass
HBsAg |
|
|
T/F: some HBV doesn't have HBeAg
|
true
|
|
|
HBe negative HBV is better/worse than positive
|
worse
|
|
|
HBe negative HBV is more/less common than positive
|
more
|
|
|
3 drugs for HBV
|
IFNa
lamivudine adefovir dipvoxil |
|
|
___ is the drug of choice for HBV.
because it causes ___, it can't be used on ___. |
IFNa
cytotoxic pts with advanced disease |
|
|
lamivudine is a ___ drug.
|
nucleoside analog
|
