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159 Cards in this Set

  • Front
  • Back

Erythroxylum coca

Common name: Cocaine
Geography: Andes Mountains in S. America
Ethnomedical uses: leaves are chewed


derivatives: tetracaine, lidocaine, procaine
Active compounds: cocaine alkaloid
Mech. of action: inhibition of local norepinephrine re-uptake -> local vasoconstriction, local anesthetic - blockade of nerve impulses

Filipendula ulmaria

Common name: meadowsweet
Geography: Eurasia
Ethnomedical use: inflammation, pain, fever
Pharmaceuticals: salicylic acid (aspirin)


inhibits cyclooxygenase which inhibits prostaglandin synthesis, reduces platelet homeostasis

Salix alba (s. helix, S. pentandra, S. praecox, S. fragilis, S. purpurea)

Common name: willow
Geography: Meditteranean, Eurasia
Ethnomedical use: analgesic, headache, anti-inflammatory, fever
Active compound - salicin -> salicylic acid when metabolized


inhibits cyclooxygenase which inhibits prostaglandin synthesis

Aspirin mechanism of action

1. blocks cyclooxygenase
2. decreases aconversion of arachidonic acid to endoperoxide
2. decreases formation of thrmoboxane A2
3. decreases prostaglandin synthesis
4. decreases inflammation

Dioscorea spp (Dioscorea mexicana, Dioscorea composita)

Common name: wild yam
Geography: Mexico
Ethnomedical use: anti-inflammatory, fish poisons, asthma


precursor of glucocorticoids


Blocks cytokine production>>>inhibits prostoglandin synthesis

Cinchona officinalis

Quinine tree


Geography: S. American rainforest
Therapeutic use: Rheumatoid arthritis
Chemical compound: hydroxychloroquine


anti-inflammatory, treat tachyarrhythmias, anti-malaria


agonist at TRPA-1 wasabi receptor

Harpagophytum procumbens

Geography: Southern Africa in Kalahari desert
Mechanism of action - anti-inflammatory
Therapeutic use - lower back pain, hip pain, and knee pain
active molecule - harpagoside

Capsicum annuum

Common name: Chile pepper, cayenne pepper
Geography: Tropical America
Ethnomedical use of fruit:
topically as analgesic for - arthritis, inflammation, neuralgias
orally as a stimulant and anti-microbial
active compound - capsaicin


TRPV-1 capsaicin receptor agonist

capsicum frutescens

Common name: Tabasco pepper
Geography: Tropical America
Ethnomedical use of fruit:
topically as analgesic for - arthritis, inflammation, neuralgias
orally as a stimulant and anti-microbial
active compound - capsaicin

Syzygium aromaticum

Common name: clove oil
Geography: Native to Asia
Mech. of action: clove oil stimulates capsaicin receptors
Medical use: used topically on skin as analgesic and is applied topically to gums to treat toothaches

Berberis aquafolium

Common name: Oregon Berry
Geography: Northwest USA
Therapeutic use: Psoriasis, AIDS, cholera, giardia

Eucalyptus globulus

Geography: Australia
Ethnomedical use: topically as analgesic
Phyomedicines - oil, cineole (eucalyptol)


Agonist at TRPM8 menthol pain receptor


asthma upper resp

Aloe vera

Common name: aloe
Geography:
vera - Southwest Arabia
spp - South, East, and North Africa, Arabia
Ethnomedical use: treat skin burns and skin infections

Hamamelis virginiana

Common name: witch hazel
Geography: eastern N. America
Ethnomedical/Therapeutic uses: topical application to treat bruises, hemorrhoids, varicose veins, aftershave

Arnica montana

Common name: arnica
Geography: N and C Europe
Ethnomedical/Therapeutic use: topically applied to treat skin inflammation, bruises, blunt injuries, rheumatism

Arnica fulgans

Common name: arnica
Geography: North America
Ethnomedical/Therapeutic use: topically applied to treat skin inflammation, bruises, blunt injuries, rheumatism

Calendula officinalis

Common name: Marigold, calendula
Geography: Mediterranean area
Therapeutic uses: topically applied to treat skin inflammation, skin infections, and for wound healing

Avena sativa

Common name: oats
Geography: Europe
Therapeutic use: topically to treat skin itching/puritis

Carica papaya

Common name: papaya
Geography: Tropical America
Mech. of action - protease enzymes help enzymatically digest protein and debride necrotic wound tissue and enhance wound healing
Therapeutic use: topically applied to debride necrotic tissue and enhance wound healing
taken orally to enhance digestion

Ananas comosus

Common name: pineapple, ananas
Geography: South America
Cultural origins: Tupi Indians in S. America
Mech. of action - protease enzymes help enzymatically digest protein and debride necrotic wound tissue and enhance wound healing
Therapeutic use: topically applied to debride necrotic tissue and enhance wound healing
take orally to treat digestion and enhance digestion

Gossypium spp.

Common name: Cotton
Geography: China
Ethnomedical use: birth control in males
Active compound: gossypol
Mech. of action: inhibits sperm formation
Modern medical use: male contraceptive

Serenoa repens

Common name: saw palmetto
Geography: Native to Florida
Ethnomedical use: fruits used by Native Americans to treat benign prostatic hypertrophy and as an aphrodisiac

Vitex agnus-castus

Common name: chasteberry
Geography: native to southern Europe
Mech. of action - stimulation of gonadotropic releasing hormone in hypothalamus and increases release of LH and progesterone; decreases estrogen level
Therapeutic uses: reduce sexual desire, pre-menstrual stress syndrome

Oenothera biennis

Common name: evening primose
Geography: Europe
Ethnomedical uses: pre-menstrual syndrome, menopausal hot flashes

Panax ginseng

Common name: ginseng
Geography: Korea, NE China
Ethnomedical use:
tonic to enhance mood, physical performance, intellectual performance, improve metabolic functions, and as an aphrodisiac, upper respiratory diseases

panax quinquefolius

Common name: ginseng
Geography: eastern N. America
Ethnomedical use:
tonic to enhance mood, physical performance, intellectual performance, improve metabolic functions, and as an aphrodisiac

Cimicifuga racemosa

Common name: black cohosh
Geography: N. America
Ethnomedical use: pre-menstrual syndrome and menopausal hot flashes

Hevea brasiliensis

Common name: para rubber
Geography: S. America
Cultural origins: multiple Amazonian indigenous groups
Ethnobotanical use: utensils
Mech. of action - mechanical protection
Modern medical uses: rubber surgical gloves, condoms
Saponaria officinalis

Common name: soapwort
Geography: Europe
Ethnomedical use: galactogogue

Trigonella foenum-graecum

Common name: fenugreek
Geography: Europe
Ethnomedical use: galactogogue

Galega officinalis

Common name: goat's rue
Geography: Europe to Iran
Ethnomedical use: Type 2 diabetes


reduction of insulin resistance

Larrea divaricata/ tridentata

Common names:
subsp. tridentata (creosote bush) - deserts of SW N. America
subsp. divaricata - deserts of S. America
Ethnomedical use: Type 2 diabetes, kidney disease, reduction of insulin resistance

Momordica charantia

Common name: bitter melon, bitter cucumber
Ethnomedical use: fruit taken orally to treat type 2 diabetes

Vernonia amygdala

Common name: bitter leaf


Africa
Uses; leaf eaten as food, tonic, and to treat type 2 diabetes, reduction of insulin resistance, malaria

opuntia basileris, opuntia spp.

Common names: prickly pear cactus, beaver tail, nopale
Geography: Mexico, SW USA
Ethnomedical use: pad-shaped stems taken orally by indigenous groups to treat type 2 diabetes
mech. of action - reduces sugar absorption by the intestine, reduction of insulin resistance

Morinda citrifolia

Common name: noni, nono
Geography: SE Asia
Ethnomedical use: fruit used to treat type 2 diabetes, arthritis, and is applied topically to treat skin boils, reduction of insulin resistance

Ravenala madagascariensis
Geography: W. Africa
treats type 2 diabetes
annona senegalensis
Geography: W. Africa
treats type 2 diabetes
aframomum melegueta
Common name: guinea peper
Geography: W. Africa
Use; treat type 2 diabetes
anacardium occidentale
Common name: cashew
Geography: S. America
Use: treat type 2 diabetes
mangifera indica

Common name: mango
Geography: Asia
Use: treat type 2 diabetes

Camellia sinensis

Common name: Tea
Use: tea drinkers have a lower risk of heart attacks than people who do not drink tea; anti-oxidant, reduction of insulin resistance

Lycopersicum esculenta

Common name: tomato


South America
Use: antioxidant

Glycine max

Common name: soybeans
Geography: China
Uses: phytoestrogenic effects on humans


reduce cardiovascular disease

melilotus officinalis

Common name: sweet clover
Goegraphy: Eurasia, naturalized in N. America
Ethnomedical uses: carminative, spasmolytic
Modern medical use: anti-coagulant

potentilla fragariodes

Common name: cinquefoil
Ethnomedical use: hemostatic
Therapeutic use: hemostatic

Allium sativum

Common name: garlic
Geography: Eurasian
Therapeutic use: anti-hyperlipidemic, anti-microbial


Ethnomedical use: antimicrobial, antihyperlipidemic, aphrodisiac


Agonist at TRPA1 wasabi receptor

Avena sativa

Common name: oats
Geography: Meditteranean
Mech. of action - oat bran in diet binds lipids in GI tract and reduces absorption

Pinus spp.

Geography: Northern hemisphere
Therapeutic uses: benecol margarin is eaten as a food to lower cholesterol

Digitalis lanata and D. purpurea

Common name: foxglove
Goegraphy: Europe
Ethnomedical uses: cardiac stimulant, congestive heart disease

Acokantheran oppositifolia

Geography: E and S Africa
Ethnomedical use: arrow poison from wood

Strophanthus gratus

Geography: Africa
Ethnomedical use: poison from seeds


tx for CHF

Convallaria majalis
Common name: lily of the valley
Geography: europe
Modern medical use: cardiotonic
Adonis vernalis
Common names: false hellabore from Europe
Ethnomedical use: heart condition
Modern medical use: cardiotonic
Erythroxylum coca
Common name: coca
Geography: Andes Mountain, S. America
Ethnomedical use: leaves used as a stimulant, cardiac stimulant, enhance endurance, and appetite suppressant

Chinchona officinalis

Geography: Native to S. America introduced to Africa and Asia
Ethnomedical use: fever

Atropa belladonna

Common name: belladonna
Geography: Europe
Chemical class: alkaloid
Pharmaceuticals: atropine, scopolamine, hyoscyanine, treat bradycardia

Crataegus monogyna, C. laevigata, C. oxyacantha, C. spp

Common name: hawthorne
Ethnomedical use: leaf and flower prepartions of this small tree taken to treat coronary artery disease, angina, circulatory disorders
Mech. of action - dilation of coronary arteries
Modern medical uses: coronary artery disease, angina, circulatory disorders

Ammi visnaga

Geography: Mediterranean environments in S. Europe, N. Africa
Cultural origins: Berber in N. Africa
Ethnomedical uses: fruit extract taken orally to treat angina pectoris and asthma
mech. of action - increased blood flow to coronary arteries to treat angina pectoris, prevents release of histamine-> asthma

Theobroma cacao

Common name: chocolate
Therapeutic uses: smooth muscle relaxant, angina pectoris, coronary artery dilator, myocardial stimulant, diuretic

Rauvolfia serpentina

Common name: rauvolfia
Geography: India, Indomalasia
Ethnomedical use: anti-hypertensive, sedative, tranquilizer, anti-psychotic, damages storage vesicles reducing norepinephrine levels

Rhododendron molle
Geography: China
Ethnomedical uses: hypotensive, insect repellent
Modern medical uses: anti-hypertensive, tranquilizer
Veratrum album
Common name: white hellebore
Modern medical use: anti-hypertensives
Stephania tetrandra

Geography: Old World
Modern medical use: anti-hypertensive, sedative

Tanacetum parthenium

Common name: feverfew
Geography: SE Europe
Ethnomedical use: Migraine headaches, fever

Aesculus hippocastanum

Common name: horse chestnut
Geography: Europe to S. Asia
Ethnomedical use: seeds used in Europe to treat varicose veins and chronic venous insufficiency

Pausinystalia johimbe

Common name: Yohimbine
Ethnomedical use: taken orally as an aphrodisiac in W. Africa by many different ethnolinguistic groups
Mech. of action - competitve blockade on adrenergic receptors
Therapeutic uses: taken orally as an aphrodisiac and to treat impotence

Papaver somniferum

active compound: Papaverine
Mech. of action: vasodilator, smooth muscle relaxant, reduce release of substance P (pain receptors), endorphins on morphine receptors, treat tachyarrhythmias


Ethnomedical: used for cough, drug
Therapeutic use: penis injection of papaverine, produce prolonged penile erections to treat impotence, used as an aphrodisiac

Colchicum autumnale

Common name: crocus
Geography: Europe to N. Africa
Ethnomedical uses: gout, pain, inflammation
Mech. of action - causes a doubling of chromosomes by disorganizing the spindle mechanism at mitosis
Modern medical uses - colchine as anti-tumor, lupus, arthritis, gout

Podophyllum peltatum and p. hexandrum

Common name: May apple
Geography:
p. peltatum - N. America
p. hexandrum - Himalayas
Ethnomedical uses:
warts, laxative, cathartic, emetic, helminthic infections, cancer, genital infections

Catharanthus roseus

Common name: Madagascar periwinkle, rosy periwinkle
Geography: native to Madagascar
Ethnomedical uses: Type 2 diabetes, Hodgekin's disease

Taxus brevifolia

Common name: pacific yew
Geography: Northern CA up through pacific northwest
Ethnomedical use: skin cancers, breast cancers
Mech. of action - anti-microtubule and anti-mitotic

Viscum album

Common name: European mistletoe
Cultural origins: Europe
Ethnomedical uses: joint inflammation, malignant tumors

Manihot esculenta

Common names: cassava, manihot
Geography: Amazon basin, S. America
Ethnomedical uses: leaves and roots eaten as food and to treat malaria

chinchona officinalis, c. ledgeriana

Common names: quina, chinchona, calisaya bark, Jesuits' bark, yellow bark, Ledger bark, crown bark, Loxa bark
Geography: Native to S. America
Ethnomedical use: fever

Artemisia annua

Geography: China, Vietnam, Asia
Ethnomedical use: plant leaves treat malaria for thousands of years in china and vietnam, anti-malaria

Artemisia maritima

Common name: wormseed
Ethnomedical use: anti-helminthic
Mech. of action - anti-helminthic
Therapeutic use: ascaris worm intestinal infections

Berberis vulgaris and B. aquafolium

Common names/Geography:
barberry in Europe
Oregon berry in northwest USA
Ethnomedical uses: dysentery, diarrhea, skin disease, psoriasis

cinnamomum zeylanicum

Common name: Cinnamon
Origin: Asia
Bark extract taken orally to treat gastritis and stomach and duodenal uclers by inhibiting the bacteria Helicobacter pylori, reduction of insulin resistance

Hydrastis canadensis

Common name: goldenseal
Geography: N. America
Cultural originas: multiple Native American groups
Ethnomedical use: astringent, anti-infective, strengthen mucosal membranes in upper respiratory tract
mech. of action - antimicrobial


Allium sativum

Common name: garlic
Ethnomedical use: antimicrobial, antihyperlipidemic, aphrodisiac
Therapeutic use: antimicrobial, anti-hyperlipidemic

Zingiber officinalis

Common name: ginger
Geography: ASia
Rhizome tuber taken orally or as a vapor to treat respiratory virus


agonist at capsaicin receptor

Sambucus nigra

Common name: Elderberry
Origin: Mediterranean region
Fruit and flower extracts taken orally to treat upper respiratory viruses

Panax ginseng

Common name: ginseng
Origin: China, Korea
Rhizome extract taken orally to treat upper respiratory viruses

Echinacea spp.

Common names: echinacea, coneflower
Geography: grasslands and open fields of Great Plains of USA
Cultural origins: American indians including Sioux, Pawnee, Blackfoot
Ethnomedical uses:
infections, immunostimulant, respiratory infections, intestinal infections, urinary tract infections
Mech. of action: immunostimulation by increasing leukocytes, stimulate phagocytosis, and increase cytokines in peripheral blood macrophages
Therapeutic uses: immunostimulant and respiratory infections

Illicium verum

Common name: Star Anise
Origin: China and Vietnam
Modern medical use: taken orally to treat avian flu, stimulate digestive enzymes

Thymus vulgaris

Common name: thyme
Geography: Mediterranean
Ethnomedical uses: expectorant, treating lung infections, bronchospasms, fungal infections, antibacterial

coffea arabica

Origin: Northeast Africa
Therapeutic use: may reduce the development of liver cirrhosis, reduction of insulin resistance

silybum marianum
Common name: milk thistle
Geography: Europe
Ethnomedical uses: liver disorders, hepatitis
Therapeutic uses: anti-hepatotoxic, prevent hepatitis, antedote to Amanita hepatic poisoning
ephedra sinica, e. equisetina, e. trifurca
Common names:
e. sinica, e. equisetina - Ma Huang
e. trifurca - mormon tea
Ethnomedical uses: asthma, sinusitis, stimulant

ammi visnaga

Common name: visnaga
Geography: Mediterranean
Cultural origins: Berber in N. Africa
Ethnomedical uses: angina, asthma

origanum vulgare

Common name: oregano
Ethnomedical uses: tea from leaves, upper respiratory infection, rhinitis

Glaucium flavum

Therapeutic use: antitussive

Arsidia japonica

Ethnomedical use: chronic bronchitis
Therapeutic use: antitussive

Plantago afra, p. ovata

Common name: psyllium
Ethnomedical use: seeds and husk seeds used as laxative to treat constipation 1-3 days

senna alexandrina, cassia senna, senna augustifolia, senna spp.

Trop America


Common names: senna, Tinnevelly senna pods
Ethnomedical use: treat constipation
mech. of action - stimulant laxative- 8hrs


antibacterial

Rhamnus spp., rhamnus purshianus, r. frangula

Common names:
purshianus - cascara sagrada bark
frangula - frangula bark
mec. of action - stimulant laxative-8hrs
therapeutic uses - laxative to treat constipation

ricinus communis

Common name: castor oil
Mech. of action - osmotic laxative
Therapeutic uses - low dose - laxative 1-3 hrs
high dose - cathartic

mentha piperita

Common name: peppermint
Geography: Eurasia
Ethnomedical use: digestive problems with diarrhea and/or constipation
intestinal spasms
irritable bowel syndrome


agonist at TRPM8 menthol pain receptor

berberis vulgaris, B. aquafolim, berberis spp.

Common name/Geography:
B. vulgaris - barberry, Europe
B. aquafolium - Oregonberry, USA
Therapeutic uses:
dysentery caused by bacteria and Entamoeba histolytica
Giaradia lamblia - diarrhea
secretory diarrhea including cholera
AIDS related diarhea

Fraxinus rhynchophylla
Common name: ash
Ethnomedical use: dysentery

Hemsleya amabilis

Ethnomedical use: dysentery
Modern medical use: bacillary dysentery, anti-pyretic

Croton lechleri

Common names: sangre de drago, sangre de grado
Geography: western Amazon basin, S. America
Ethnomedical use:
diarrhea
herpes skin infections
wound healing
tuberculosis
pneumonia

Pscyhotria ipecacuanha

Brazil


emetic


intestinal amoebas

Alzheimer's disease (cause)

Oxidation


free radicals in the brain cause elements in the brain to lose electrons (free radical scaverngers pick up these radicals: anti-oxidants)

Antioxidants

blueberries, cumin, tea, coffee

Vaccinium spp

Blueberries


anti-oxidant rich fruit


North America


reduce risk of alzheimers

Curcuma longa

tumeric


India


Ethnomedical uses: cooking, infection, enhance brain function


reduces developments of senility and enhances cog function

Cannabis sativa

THC and Cannabindiol (CBD)


analgesic, reduces risk of dementia, treat nausea


cannabinoid receptors (CB1 and CB2)

Phyllomedusa sauvage

Frog


Amazon


Demorphin extracted from its back 40x stronger than morphine, less addictive effects

Gaultheria procumbens

wintergreen


Eastern North America


inhibits cyclooxygenase which inhibits prostaglandin synthesis

Betula lenta

sweet birch


Eastern North America


inhibits cyclooxygenase which inhibits prostaglandin synthesis

Cinnamomium camphor

camphor oil


Asia


agonist at TRPM8, menthol pain receptor

Piper nigrum

India


agonist at capsacin receptor pain pathway

Eutrema wasabi

Asia


Agonist at TRPA1 wasabi receptor

armoracia rusticana

horse radish


SE Europe & Western Asia


Agonist at TRPA1 wasabi receptor

Brassica nigra/ juncea/oleracea

mustard


Asia


Agonist at TRPA1 wasabi receptor


oleracea reduces risk of cancer

allium cepa

Asia


agonist at TRPA-1 wasabi receptor

Acemelia oleraceae

toothache plant


South America


salad vegetable, analgesic

COX-1 and COX-2 enzymes

target of anti-inflammatory drugs COX 1 has homeostatic function (don't want to inhibit) gastrointestinal tract stuff


COX 2-responsible for inflammation and pain (want to inhibit) NSAIDs do this well


Tiger Balm

includes hot and cold receptors

Pancreas Beta cells (B cells)

produce insulin

Syndrom X

Metabolic syndrome that develops secondary to insulin resistance


high triglycerides, low HDL, high blood clotting, high BP, high Coronary artery disease

Magnifera indica

mango


India


Type 2 diabetes

Gymnema sylvestre

Cowplant


India/ Sri Lanka


diminish taste bud perception of sweetness, appetite suppressant

Thaumatococcus daniellii

miracle berry


West Africa


turn non-sweet foods sweet

Synsepalum dulcificum

miracle fruit


West africa


make taste sweet

Stevia rebaudiana

South America


non-caloric sweetener

Omega 3 fatty acids

flaxseed oil (Europe)


walnut oil (Asia)


hemp oil (Asia)


salmon oil



reduce cardiovascular disease

monounsaturated fats

Olive oil


canola oil


peanut oil


Avocado oil


Sesame oil


Almond oil



reduce cardiovascular disease

Glycine max

China


reduce cardiovascular disease

Dasiphora fruticosa

golden harhack, cinqufoil



hemeostasis

Nerium oleander

oleander


Mediterranean


increases Ca2+ treat CHF

Cardiac Glycoside Arrow Poison

Africa


Strophanthus gratus


Acokanthera oppositifolia

Adrenergic Alpha 1 receptor

arteriole construction


lowers gland secretion


lowers intestinal motility

Adrenergic Beta 1 receptors

increase heart rate/ contractility/ velocity


cardiac automaticity


increases renin secretion by kidney=> increases blood pressure

Adrenergic Alpha-2 receptors

lowers secretion of insulin from beta cells in pancreas

Camptotheca acuminata

Happy Tree


China


inhibits nuclear DNA

Fungus

tamari


miso


cheese

Meialeuca alternifolia

Australia


tea tree oil


antifungal, antibacterial

Lyna vesicatoria

Spanish fly & other blister beetles


Europe


Tx of papilloma virus

Chrysanthemum cinerarifolium

Europe


insect repellent

Corymbia citriodora

Australia


insect repellent

Azadirachta indica

India


insect repellent

Astragalus

goat's thorn


China


prevents telomere shortening


being developed to tx HIV/ AIDS

Uncaria tomentosa

South America


immunostimulant


treat viral infections


cat's claw

Urtica dioica

nettle


Europe


Allergic rhinitis

Apnea in premature infants

coffee. tea, chocolate, cola acuminate, paullina cupana

Matricaria recutita

Chamomille tea


Europe


treats stomach discomfor

Psidium guajava

guava


trop America


Treats diarrhea

Oryza sativa

rice, rice water


Asia


Anti-secretory mech to tx diarhea

Angelica sinesis

angelica


Asia


stimulates digestive enzymes

Elettaria cardamomum

cardamon


Asia


stimulates digestive enzymes

Foeniculum vulgare

anise


Mediterranean


stimulates digestive enzymes

Pimpinelia anisum

anise


Mediterranean and SW Asia


stimulates digestive enzymes

Mentha spicata

spearmint


Europe


stimulates digestive enzymes

Ursodeoxycholic

Mammal gall bladders


Worldwide


Treats cirrhosis, breaks down fats

Cynara cardunculus

artichoke


Europe


digestive gall bladder stimulant

Silybum marianum

Europe


protects liver against toxicity