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32 Cards in this Set

  • Front
  • Back
Three functions of hypothalamus?
1)limbic
2) endocrine
3) autonomic
What are the specialized features of the hypothalamus?
blood monitoring capabilities
-fenestrated capillaries
-osmoreceptors
-glucoreceptors
2)feedback loops for anterior and posterior pituitary
Where are the osmoreceptors and glucoreceptors in the hypothalamus?
osmoreceptors-supraoptic nucleus
glucoreceptors - ventromedial nucleus
What are the components of the hypothalamus??
ventrally (under brain) - tuber cinereum and median eminence which opens into pituitary stalk with the mamillary body caudal
What is around the hypothalamus?
anterior-lamina terminalis, optic chiasm,
around it - ventral portion of third ventricle
What are the two ways you can divide the hypothalamus?
1) anterior-tuberal-posterior
2) periventricular - lateral-
Whats the anterior region?
anterior - rostral - preoptic, suprachiasmatic, supraoptic, paraventricular, sexually dimorphic
Whats in tuberal region?
location: above tuber cinereum/infundibulum
nuclei: dorsomedial, ventromedial, lateral hypothalamic area, arcuate
Whats in the posterior region?
posterior hypothalamic area
mamillary complex
What is more clustered or diffuse the periventricular zone or the lateral zone?
periventricular zone - clustered
lateral zone- more diffuse
What are the nuclei that help the hypothalamus control the endocrine system? (5)
1) paraventricular
2)preoptic
3) arcuate
4) supra optic
5) suprachaismatic
What rleases the releasing hormones and dopamine? (3)
paraventicular, preoptic and arcuate
Where are releasing factors released into hypothalamo-hypophyseal portal system?
arcuate nucleus
What is the sexually dimorphic area?
preoptic nucleus thats three times larger in males than females
What produces oxytocin and vasopressin? (2)
supraoptic and paraventricular nuclei
What is the biological clock?
suprachiasmatic nucleus which lies immediately above the optic chiasm and receives retinal input
What system does the anterior and posterior nuclei of the thalamus regulate?
symapthetic - posterior
parasympathetic - anterior
What effects does the posterior nuceli have on C.O., BP, vasculature, GI perstalsis, heat?
sympathetic
CO-accelerate
BP - elevate
vasculature - vasoconstrict
GI - cessation
thermal - heat conservation
What effect does the anterior nuclei have on C.O., BP, vasculature, GI peristalsis and heat?
parasympathetic
CO-decreases
BP - lowered
vasculature - vasodilate
GI - increases
thermal - hyperthermia
What nuclei of the hypothalamus have effect on food intake?
1)dorsomedial
2)ventromedial
3)laterla nuclei
What is the satiety center?
ventromedial nuclei
What happens if you have a lesion in the ventromedial nuclei?
obesity and rage
What is the appetite stimulating center?
lateral nuclei
What happens if you lesion the lateral thalamic nuceli?
loss of appetite
What is the area involved in food intake regulation?
lateral nuclei which has receptors for leptn
What is the action for leptin?
reduce appetite
How is the hypothalamus involved in the limbic system?
integrates behavioral and emotional responses arising from the limbic system with autonomic functions to produce integrated/coordinated autonomic control and behavior
What is the structure that ties the hypothalamus into the limbic system?
mamillary complex,
input: hippocampus via fornix
output: anterior thalamus via mamillothalamic tract
What is Wernicke-Korsakoff's syndrome?
hemmorhages in mamillary nuclei that cause anterograde amnesia
What are the afferent connections of the hypothalamus? (6)
1)fornix -precomissural bundle and post comissural bundles
2) medial forebrain bundle
3) ventral norepinephrine bundle
4) amygdala - stria terminalis and ansa peduncularis
5) retinal fibers
6) GVA and SVA from solitary nuclei via mamillary peduncle
What are the efferent connections of the hypothalamus?
1)mamillary bodies- mamillothalamic and mammilotegmental
2) dorsal longitudinal fasiculus to brainstem
3)hypothalamo-hypophyseal tract
4) hypothalamo-hypophyseal portal
Which of the hypothalamo-hypophyseal systems go to anterior vs posterior lobe?
posterior - hypothalamohypopjhyseal tract
anterior - hypothalamohypophyseal portal