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42 Cards in this Set

  • Front
  • Back
What is the pneumonic for tissues derived from neural crest cells?
MOTEL PAASS
M- melanocytes
O- odontoblasts
T- tracheal cartilage
E- enterochromaffin cells
L- laryngeal cartilage
P- parafollicular cells, pseudounipolar cells
A- all ganglia, adrenal medulla
S- schwann cells
S- spiral membrane
What is the only pituitary hormone under inhibition all the time?
prolactin
What stimulates PRL release?
nipple stimulation
What inhibits PRL release?
dopamine
What are the 4 dopamine agonists used to treat Parkinson's?
L-dopa/carbidopa, bromocriptine, selegyline, amantidine
How does selegyline work?
it increases extracellular dopamine by selectively inhibiting MAO-B
What is the class of drugs that blocks dopamine (D-2 rec)?
phenothiazines
What do all the phenothiazines end in?
"azine"
What is used for antiemetics in adults?
prochlorperazine
What is the most common antiemetic in children?
promethazine
What phenothiazine is used for antipsychotic treatment?
thioridazine
What is the major side effect of thioridazine?
pigment retinopathy
Where is the chemotactic trigger zone?
under the 4th ventricle- called the area postrema
Haloperidol is what kind of drug?
dopamine blocker
What is haloperidol used for?
antipsychotic, schizophrenia, psycosis
What is the 4 four rules for antipsychotics?
4 h acute dystonia, 4 d akinesia, 4 wk akathisia, 4 mon tardive dyskinesia
When would you choose an atypical for treatment?
if the patient has had extrapyramidal side effects before
What is the 3 atypical pneumonic?
It's not atypical for OLd CLOsets to RISPER

olnazapine, clozapine, risperidone
What does toxicity of clozapine cause?
agranulocytosis and seizures
What are the side effects of olanzapine?
weight gain and diabetes
What can resperidone cause?
neuroleptic anesthesia
What is the most common pituitary tumor?
nonfunctional (chromophobic) adenoma
What is the most common functional pituitary tumor?
prolactinoma
What are ALL pituitary tumors associated with?
high prolactin levels
High PRL causes what?
galactorrhea and amenorrhea
What 2 hormones does high PRL levels inhibit?
GnRH and TRH
In utero, what does the thyroid control?
hormones, growth, differentiation
After birth, what does the thyroid control?
only growth
What is the #1 cause of hypothyroidism?
iodine deficiency
What is the #1 cause of hypothyroidism in women?
Hashimoto's
What are the markers for Hashimoto's?
antithyroglobulin and antiperoxidase
What is the treatment for hypothyroidism?
give T4 (thyroxine) or T3 (L-thyronine)
Parkinson's is caused by what?
deterioration of neurons in the substantia nigra
What is the pneumonic for treatment of Parkinson's?
BALSA
B- bromocriptine
A- amantidine
L- L-dopa/carbidopa
S- selegiline
A- benztropine (antimuscarinic)
What are the 3 growth periods for a child?
0-2
4-7
puberty
What is the #1 cause of hyperthyroidism?
Grave's
How old are Grave's patients?
< 50
What are the markers for graves disease?
antiTSH
What causes hyperthyroidism in people > 50?
plummer's syndrome- toxic multinodular goiter
What is seen in Plummer's Syndrome?
one hot area of iodine uptake
What is the treatment for hyperthyroidism?
propanolol- to treat high HR
propylthiouracil- blocks peroxidation
methimazole- blocks peroxidation
I-131- destroys thyroid tissue
thyroxine- thyroid hormone replacement
What thyroid treatment would you give to pregnant women? Which would you not?
propylthiouracil- to prego
methimazole- not to prego