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42 Cards in this Set
- Front
- Back
What is the pneumonic for tissues derived from neural crest cells?
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MOTEL PAASS
M- melanocytes O- odontoblasts T- tracheal cartilage E- enterochromaffin cells L- laryngeal cartilage P- parafollicular cells, pseudounipolar cells A- all ganglia, adrenal medulla S- schwann cells S- spiral membrane |
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What is the only pituitary hormone under inhibition all the time?
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prolactin
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What stimulates PRL release?
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nipple stimulation
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What inhibits PRL release?
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dopamine
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What are the 4 dopamine agonists used to treat Parkinson's?
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L-dopa/carbidopa, bromocriptine, selegyline, amantidine
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How does selegyline work?
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it increases extracellular dopamine by selectively inhibiting MAO-B
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What is the class of drugs that blocks dopamine (D-2 rec)?
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phenothiazines
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What do all the phenothiazines end in?
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"azine"
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What is used for antiemetics in adults?
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prochlorperazine
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What is the most common antiemetic in children?
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promethazine
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What phenothiazine is used for antipsychotic treatment?
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thioridazine
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What is the major side effect of thioridazine?
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pigment retinopathy
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Where is the chemotactic trigger zone?
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under the 4th ventricle- called the area postrema
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Haloperidol is what kind of drug?
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dopamine blocker
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What is haloperidol used for?
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antipsychotic, schizophrenia, psycosis
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What is the 4 four rules for antipsychotics?
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4 h acute dystonia, 4 d akinesia, 4 wk akathisia, 4 mon tardive dyskinesia
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When would you choose an atypical for treatment?
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if the patient has had extrapyramidal side effects before
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What is the 3 atypical pneumonic?
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It's not atypical for OLd CLOsets to RISPER
olnazapine, clozapine, risperidone |
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What does toxicity of clozapine cause?
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agranulocytosis and seizures
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What are the side effects of olanzapine?
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weight gain and diabetes
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What can resperidone cause?
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neuroleptic anesthesia
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What is the most common pituitary tumor?
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nonfunctional (chromophobic) adenoma
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What is the most common functional pituitary tumor?
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prolactinoma
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What are ALL pituitary tumors associated with?
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high prolactin levels
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High PRL causes what?
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galactorrhea and amenorrhea
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What 2 hormones does high PRL levels inhibit?
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GnRH and TRH
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In utero, what does the thyroid control?
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hormones, growth, differentiation
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After birth, what does the thyroid control?
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only growth
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What is the #1 cause of hypothyroidism?
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iodine deficiency
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What is the #1 cause of hypothyroidism in women?
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Hashimoto's
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What are the markers for Hashimoto's?
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antithyroglobulin and antiperoxidase
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What is the treatment for hypothyroidism?
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give T4 (thyroxine) or T3 (L-thyronine)
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Parkinson's is caused by what?
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deterioration of neurons in the substantia nigra
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What is the pneumonic for treatment of Parkinson's?
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BALSA
B- bromocriptine A- amantidine L- L-dopa/carbidopa S- selegiline A- benztropine (antimuscarinic) |
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What are the 3 growth periods for a child?
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0-2
4-7 puberty |
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What is the #1 cause of hyperthyroidism?
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Grave's
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How old are Grave's patients?
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< 50
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What are the markers for graves disease?
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antiTSH
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What causes hyperthyroidism in people > 50?
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plummer's syndrome- toxic multinodular goiter
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What is seen in Plummer's Syndrome?
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one hot area of iodine uptake
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What is the treatment for hyperthyroidism?
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propanolol- to treat high HR
propylthiouracil- blocks peroxidation methimazole- blocks peroxidation I-131- destroys thyroid tissue thyroxine- thyroid hormone replacement |
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What thyroid treatment would you give to pregnant women? Which would you not?
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propylthiouracil- to prego
methimazole- not to prego |