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8 Cards in this Set
- Front
- Back
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Hypothalamus |
Produces hypophysiotropins and neurohormones that regulate Anterior Pituitary hormone secretions. |
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Geoffrey W. Harris |
1913-1971 Geoffrey Harrisis considered by many to be the "father" of neuroendocrinology. Harris, the Dr. Lee's Professor of Anatomy at Oxford University, is credited with showing that the anterior pituitary gland of mammals is regulated by hormones secreted by hypothalamic neurons into the hypothalamohypophysial portal circulation. By contrast, the hormones of the posterior pituitary gland are secreted into the systemic circulation directly from the nerve endings of hypothalamic neurons. |
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Median eminence |
Median Eminence is the beginning of the pituitary stalk (infundibulum), just below the 3rd ventricle. Part of it, is outside the Blood-Brain-Barrier. As such,it is a Circumventricular Organ (CVO), and systemic hormones can regulate it. Site of Primary Hypothalamic-Hypophysial Portal Capillaries |
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Anterior pituitary regions |
Pars Distalis: the majority of the AP were most hormones are produced. Includes chromophores and chromophil cells. Chromophils are divided into acidophilus and basophils. Secondary capillary bed is within pars distalis Pars Tuberalis: Forms par of the heath extending up form the pars distills. Poorly understood. may be responsible for receiving melatonin signaling from the pineal gland.( just for the pituitary) Pars intermedia: Site between the pars distalis and the poster pituitary. Sight of MSH production but is very small or absent in adult humans. |
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HypophysiotropicNeurons |
Neurons in the hypothalamus that release factors to communicate with the anterior pituitary through the superior hypophyseal artery primary portal circulation. |
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Neurohypophyseal Neurons |
Neurons with cell bodies in the supra-optic and paraventricular nucleus of the hypothalamus that have axons that extend down the posterior pituitary (pars nervosa) and release Vasopressin (ADH) and Oxytocin onto the inferior hypophysial artery. |
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Short Portal vessels |
Small vessels that communicate between posterior and anterior lobes. |
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TRH |
1st Hypophysiotropic Hormone Thyrotropin releasing hormone |
